Anti-IGF1 Receptor Rabbit pAb servicebio GB111631-100

$50.00
In stock
SKU
GB111631-100

 

Product Information

Protein full nameInsulin-like growth factor 1 receptor
SynonymsInsulin-like growth factor I receptor, IGF-I receptor, CD221, MGC142170, JTK13, CD221 antigen, IGFIRC, Insulin like growth factor 1 receptor precursor
Uniprot IDQ60751
ImmunogenKLH conjugated Synthetic peptide corresponding to Mouse IGF1 Receptor
IsotypeIgG
Predicted MW./Observed MW.155 kDa / 95 kDa
PurityAffinity purification

Applications

Applications: WBSpecies: Human, Mouse, Rat
Dilution: 1: 500-1: 1000Positive Tissue: testis

Background

IGF1R, also named as CD221, is a receptor tyrosine kinase which mediates actions of insulin-like growth factor 1 (IGF1). IGF1R binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity, the activated IGF1R is involved in cell growth and survival control. It is crucial for tumor transformation and survival of malignant cell. IGF1R is a heterotetrameric receptor, composed of two alpha subunits (130 kDa each) and two beta subunits (~98 kDa each) .

Images

WB analysis of IGF1 Receptor(GB111631). Sample: Protein treated by RIPA Lysis Buffer (G2002). Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h. Primary antibody: 1: 500, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h.

WB analysis of IGF1 Receptor(GB111631). Sample: Protein treated by RIPA Lysis Buffer (G2002). Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h. Primary antibody: 1: 500, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h.

Storage

StorageStore at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Storage BufferPBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

 

 

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