Anti-SPZ1 Rabbit pAb servicebio GB111749-100
$50.00
In stock
SKU
GB111749-100
Product Information
| Protein full name | Spermatogenic leucine zipper protein 1 |
| Synonyms | BHLH-Zip transcription factor SPZ1, Spermatogenic Zip 1, Spz1, NYD TSP1, PP1C gamma 2, PPP1R148, Protein phosphatase 1, regulatory subunit 148 , Testis specific protein 1 |
| Uniprot ID | Q99MY0 |
| Immunogen | Recombinant protein corresponding to Mouse SPZ1 |
| Isotype | IgG |
| Predicted MW./Observed MW. | 43 kDa / 43 kDa |
| Purity | Affinity purification |
Applications
| Applications: WB | Species: Mouse, Rat |
| Dilution: 1: 500-1: 1000 | Positive Tissue: brain, kidney, testis |
Background
Spermatogenic leucine zipper protein 1 is a member of the basic helix-loop-helix (bHLH) family of transcription factors which is expressed specifically in the testis and epididymis. Studies show that SPZ1 acts downstream of mitogen-activated protein kinase (MAPK), an extracellular signal-regulated kinase 1/2 to up-regulate cell proliferation and tumorigenesis. Also, through an interaction with proliferating cell nuclear antigen (PCNA) promoter, SPZ1 induced cell proliferation concomitant with an increase in PCNA gene expression.
Images
WB analysis of SPZ1(GB111749). Sample: Protein treated by RIPA Lysis Buffer (G2002). Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h. Primary antibody: 1: 500, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h.
Storage
| Storage | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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