Anti-SIRT2 Rabbit pAb servicebio GB112450-100
$50.00
In stock
SKU
GB112450-100
Product Information
| Protein full name | NAD-dependent protein deacetylase sirtuin-2 |
| Synonyms | Regulatory protein SIR2 homolog 2, SIR2-like protein 2, mSIR2L2, Sir2l2, Sirt2 |
| Uniprot ID | Q8VDQ8 |
| Immunogen | Recombinant protein corresponding to Mouse SIRT2 |
| Isotype | IgG |
| Predicted MW./Observed MW. | 43 kDa / 43 kDa |
| Purity | Affinity purification |
| Subcellular location | Cell membrane, Cytoplasm, Nucleus |
Applications
| Applications: WB | Species: Human, Mouse, Rat |
| Dilution: 1: 500-1: 1000 | Positive Tissue: kidney, placenta |
| Applications: IHC/IF | Species: Mouse, Rat |
| Dilution: 1: 1000-1: 2000 | Positive Tissue: brain |
Background
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.
Images
WB analysis of SIRT2(GB112450). Sample: Protein treated by RIPA Lysis Buffer (G2002). Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h. Primary antibody: 1: 500, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h.
IHC analysis of SIRT2(GB112450). Sample: Mouse brain, 4% PFA (G1101) 12-24h. Antigen retrieval: Citrate buffer (pH 6.0) (G1201), 98℃, 20 min. Primary antibody: 1: 1000, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h.
IHC analysis of SIRT2(GB112450). Sample: Rat brain, 4% PFA (G1101) 12-24h. Antigen retrieval: Citrate buffer (pH 6.0) (G1201), 98℃, 20 min. Primary antibody: 1: 1000, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h.
Storage
| Storage | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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