Anti-PARC Rabbit pAb servicebio GB113044-100
$50.00
In stock
SKU
GB113044-100
Product Information
| Protein full name | Cullin-9 |
| Synonyms | CUL-9, p53-associated parkin-like cytoplasmic protein, Cul9, Kiaa0708, Parc |
| Uniprot ID | Q80TT8 |
| Immunogen | Recombinant protein corresponding to Mouse PARC |
| Isotype | IgG |
| Purity | Affinity purification |
| Subcellular location | Cytoplasm |
Applications
| Applications: IHC/IF | Species: Mouse, Rat |
| Dilution: 1: 600-1: 1200 | Positive Tissue: testis, striatum, substantia nigra |
Background
Core component of a Cul9-RING ubiquitin-protein ligase complex, a complex that mediates ubiquitination and subsequent degradation of BIRC5 and is required to maintain microtubule dynamics and genome integrity. Acts downstream of the 3M complex, which inhibits CUL9 activity, leading to prevent ubiquitination of BIRC5 . Cytoplasmic anchor protein in p53/TP53-associated protein complex. Regulates the subcellular localization of p53/TP53 and subsequent function.
Images
IHC analysis of PARC(GB113044). Sample: Mouse testis, 4% PFA (G1101) 12-24h. Antigen retrieval: Citrate buffer (pH 6.0) (G1201), 98℃, 20 min. Primary antibody: 1: 600, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h.
IHC analysis of PARC(GB113044). Sample: Mouse Striatum, 4% PFA (G1101) 12-24h. Antigen retrieval: Citrate buffer (pH 6.0) (G1201), 98℃, 20 min. Primary antibody: 1: 650, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h.
IHC analysis of PARC(GB113044). Sample: Rat substantia nigra, 4% PFA (G1101) 12-24h. Antigen retrieval: Citrate buffer (pH 6.0) (G1201), 98℃, 20 min. Primary antibody: 1: 600, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h.
Storage
| Storage | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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