Anti-CD44 Mouse mAb servicebio GB122054-100
$50.00
In stock
SKU
GB122054-100
Product Information
| Protein full name | CD44 antigen |
| Synonyms | CD44, CDW44, CSPG8, ECMR III, Epican, HCELL, Heparan sulfate proteoglycan, Hermes antigen, HUTCH I, Hyaluronate receptor, IN, MC56, MDU2, MDU3, MIC4, MUTCH I, PGP-1, PGP I, Pgp1, Phagocytic glycoprotein I, GP90 lymphocyte homing/adhesion receptor |
| Uniprot ID | P16070 |
| Immunogen | Human recombinant CD44 protein expressed in HEK293 cells |
| Isotype | IgG1, κ |
| Clone Number | 4A2B5-1 |
| Purity | Affinity purification |
| Subcellular location | Cell membrane |
Applications
| Applications: IHC/IF | Species: Human |
| Dilution: 1: 600-1: 1800 | Positive Tissue: lung adenocarcinoma, endometrial carcinoma, pancreas |
Background
CD44 is a type I transmembrane glycoprotein that mediates cell-cell and cell-matrix interactions through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands. Adhesion with HA plays an important role in cell migration, tumor growth and progression. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis.
Images
IHC analysis of CD44(GB122054). Sample: Human endometrial carcinoma, 4% PFA (G1101) 12-24h. Antigen retrieval: Citrate buffer (pH 6.0) (G1201), pressure cooker 2 min. Primary antibody: 1: 1800, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Mouse lgG (H+L) (GB23301), 1: 200, RT, 1h.
IHC analysis of CD44(GB122054). Sample: Human lung adenocarcinoma, 4% PFA (G1101) 12-24h. Antigen retrieval: Citrate buffer (pH 6.0) (G1201), pressure cooker 2 min. Primary antibody: 1: 1800, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Mouse lgG (H+L) (GB23301), 1: 200, RT, 1h.
IHC analysis of CD44(GB122054). Sample: Human pancreas, 4% PFA (G1101) 12-24h. Antigen retrieval: Citrate buffer (pH 6.0) (G1201), pressure cooker 2 min. Primary antibody: 1: 1800, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Mouse lgG (H+L) (GB23301), 1: 200, RT, 1h.
Storage
| Storage | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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