Product Information
| Protein full name | Protein CBFA2T1 |
| Synonyms | AML1T1, CBFA2T1, CDR, Cyclin D related protein, Eight twenty one protein, ETO, MTG8, MTG8b, Protein CBFA2T1 |
| Uniprot ID | Q61909 |
| Immunogen | Recombinant protein corresponding to Mouse RUNX1T1 |
| Isotype | IgG |
| Predicted MW./Observed MW. | 64 kDa / 74 kDa |
| Purity | Affinity purification |
Applications
| Applications: WB | Species: Mouse, Rat |
| Dilution: 1: 300-1: 500 | Positive Tissue: brain |
Background
Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes. Can repress the expression of MMP7 in a ZBTB33-dependent manner. Can repress transactivation mediated by TCF12 (By similarity). Acts as a negative regulator of adipogenesis.
Images
WB analysis of RUNX1T1/ETO/CDR(GB114460). Sample: Protein treated by RIPA Lysis Buffer (G2002). Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h. Primary antibody: 1: 500, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h.
Storage
| Storage | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).