Anti-PAX5 Rabbit pAb servicebio GB115495-100
$50.00
In stock
SKU
GB115495-100
Product Information
| Protein full name | Paired box protein Pax-5 |
| Synonyms | BSAP, BSAP,PAX5, paired box 5, Paired box protein Pax 5, PAX5 |
| Uniprot ID | Q02650 |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse PAX5 |
| Isotype | IgG |
| Predicted MW./Observed MW. | 42 kDa / 45 kDa |
| Purity | Affinity purification |
Applications
| Applications: WB | Species: Mouse |
| Dilution: 1: 300-1: 400 | Positive Tissue: A20 |
Background
Transcription factor that plays an essential role in commitment of lymphoid progenitors to the B-lymphocyte lineage. Fulfills a dual role by repressing B-lineage inappropriate genes and simultaneously activating B-lineage-specific genes. In turn, regulates cell adhesion and migration, induces V(H)-to-D(H)J(H) recombination, facilitates pre-B-cell receptor signaling and promotes development to the mature B-cell stage. Repression of the cohesin-release factor WAPL causes global changes of the chromosomal architecture in pro-B cells to facilitate the generation of a diverse antibody repertoire (By similarity).
Images
WB analysis of PAX5(GB115495). Sample: Protein treated by RIPA Lysis Buffer (G2002). Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h. Primary antibody: 1: 300, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h.
Storage
| Storage | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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