Product Information
| Protein full name | Recoverin |
| Synonyms | 23 kDa photoreceptor cell-specific protein, Cancer-associated retinopathy protein, Rcvrn, S-modulin, p26, Protein CAR |
| Uniprot ID | P34057 |
| Immunogen | Recombinant protein corresponding to Mouse Recoverin |
| Isotype | IgG |
| Predicted MW./Observed MW. | 23 kDa / 23 kDa |
| Purity | Affinity purification |
Applications
| Applications: WB | Species: Mouse, Rat |
| Dilution: 1: 500-1: 1000 | Positive Tissue: eye, retina |
Background
Recoverin, belonging to a family of the neuronal calcium sensor (NCS) proteins, has a restricted expression in retinal photoreceptors or neurons or neuroendocrine cells. It has been suggested to play a role in light and dark adaptation by regulating rhodopsin phosphorylation. Recently, it has been found that autoantibodies against recoverin (24 kDa) have been strongly associated with cancer -associated retinopathy (CAR) syndrome, a paraneoplastic disease of the retina.
Images
WB analysis of Recoverin(GB111620). Sample: Protein treated by RIPA Lysis Buffer (G2002). Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h. Primary antibody: 1: 500, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h.
Storage
| Storage | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).