Anti-PPIL2 Rabbit pAb servicebio GB113286-50
$50.00
In stock
SKU
GB113286-50
Product Information
| Protein full name | RING-type E3 ubiquitin-protein ligase PPIL2 |
| Synonyms | CYC4, Cyclophilin 60, Cyp 60, CYP60, hCyP 60, PPIase, PPIL2, Rotamase PPIL2 |
| Uniprot ID | Q9D787 |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse PPIL2 |
| Isotype | IgG |
| Purity | Affinity purification |
| Subcellular location | Nucleus |
Applications
| Applications: IHC/IF | Species: Mouse |
| Dilution: 1: 1800-1: 3600 | Positive Tissue: pancreas, testis, thymus |
Background
Has a ubiquitin-protein ligase activity acting as an E3 ubiquitin protein ligase or as an ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on substrates. By mediating 'Lys-48'-linked polyubiquitination of proteins could target them for proteasomal degradation. May also function as a chaperone, playing a role in transport to the cell membrane of BSG/Basigin for instance. Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity.
Images
IHC analysis of PPIL2(GB113286). Sample: Mouse pancreas, 4% PFA (G1101) 12-24h. Antigen retrieval: Tris-EDTA buffer (pH 9.0) (G1203), 98℃, 20min. Primary antibody: 1: 1800, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h.
IHC analysis of PPIL2(GB113286). Sample: Mouse testis, 4% PFA (G1101) 12-24h. Antigen retrieval: Tris-EDTA buffer (pH 9.0) (G1203), 98℃, 20min. Primary antibody: 1: 1800, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h.
IHC analysis of PPIL2(GB113286). Sample: Mouse thymus, 4% PFA (G1101) 12-24h. Antigen retrieval: Tris-EDTA buffer (pH 9.0) (G1203), 98℃, 20min. Primary antibody: 1: 1800, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h.
Storage
| Storage | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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