Anti-CD3G Antibody, Rabbit Polyclonal sinobiological 101341-T36

$143.00
In stock
SKU
101341-T36
Catalog No.SizePrice (USD)
101341-T36-5050 µL$147.96
101341-T36-100100 µL$251.64
101341-T36-200200 µL$355.32

General Information

Product nameAnti-CD3G Antibody, Rabbit Polyclonal
Validated applicationsWB (FAQ Protocol), IP (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman CD3G
ImmunogenA synthetic peptide corresponding to the C-terminus of the Human CD3G
PreparationProduced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Human CD3G, and purified by antigen affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A & Antigen Affinity
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-CD3-GAMMA Antibody; Anti-CD3GAMMA Antibody; Anti-IMD17 Antibody; Anti-T3G Antibody

Image / Experimental Information

Image 1 DescriptionAnti-CD3G rabbit polyclonal antibody at 1:500 dilution Lane A: Jurkat Whole Cell Lysate Lane B: HuT-78 Whole Cell Lysate Lane C: HL-60 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:20 kDa Observed band size:20 kDa
Image 1 Alt TextHuman CD3G Western blot (WB) 31772
Image 1 URLSource image
Image 2 DescriptionAnti-CD3G rabbit polyclonal antibody at 1:500 dilution Lane A: Jurkat Whole Cell Lysate Lane B: HuT-78 Whole Cell Lysate Lane C: HL-60 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:20 kDa Observed band size:20 kDa
Image 2 Alt TextHuman CD3G Immunoprecipitation(IP) 31773
Image 2 URLSource image

Background Information

Full NameCD3g molecule, gamma (CD3-TCR complex)
DescriptionCD3G gene encodes CD3-gamma polypeptide, which together with CD3-epsilon, -delta, and -zeta, and the TCR alpha/beta and gamma/delta heterodimers, forms the TCR-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The CD3 gamma chain has long been considered to mediate targeting to lysosomes for degradation. Defects in this gene are associated with T cell immunodeficiency. Further, it has been proposed as one of the important candidate genes for cancer development due to its pivotal roles in TCR signaling pathway.
Research Areas
  • ITIM/ITAM Immunoreceptors and Related Molecules
Related Pathways
  • T Cell Receptor Signaling Pathway
Tags
  • Cancer Immunotherapy
  • Immune Checkpoint
  • Immunotherapy
  • Targeted Therapy
References
  1. Jiang L, Xu J, Ni J, et al. A Functional Insertion/Deletion Polymorphism in the Proximal Promoter of CD3G Is Associated with Susceptibility for Hepatocellular Carcinoma in Chinese Population. DNA and Cell Biology.

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