Anti-CD40/TNFRSF5 Antibody, Rabbit Polyclonal sinobiological 10774-T54
$243.00
In stock
SKU
10774-T54
| Catalog No. | Size | Price (USD) |
| 10774-T54-100 | 100 µL | $251.64 |
General Information
| Product name | Anti-CD40/TNFRSF5 Antibody, Rabbit Polyclonal |
| Validated applications | WB (FAQ Protocol), ELISA (FAQ Protocol), ICC/IF (FAQ Protocol), IP (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human CD40/TNFRSF5 |
| Immunogen | Recombinant Human CD40/TNFRSF5 Protein (Catalog#10774-H08H) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human CD40/TNFRSF5 (rh CD40/TNFRSF5; Catalog#10774-H08H; NP_001241.1; Met1-Ala194). CD40/TNFRSF5 specific IgG was purified by Human CD40/TNFRSF5 affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-Bp50 Antibody; Anti-CDW40 Antibody; Anti-p50 Antibody; Anti-TNFRSF5 Antibody
Image / Experimental Information
| Image 1 Description | Anti-CD40 rabbit polyclonal antibody at 1:500 dilution Lane A: A431 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:30 kDa Observed band size:42 kDa |
| Image 1 Alt Text | Human CD40/TNFRSF5 Western blot (WB) 40615 |
| Image 1 URL | Source image |
| Image 2 Description | Anti-CD40 rabbit polyclonal antibody at 1:500 dilution Lane A: A431 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:30 kDa Observed band size:42 kDa |
| Image 2 Alt Text | Human CD40/TNFRSF5 Immunofluorescence(IF) 40616 |
| Image 2 URL | Source image |
| Image 3 Description | Anti-CD40 rabbit polyclonal antibody at 1:500 dilution Lane A: A431 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:30 kDa Observed band size:42 kDa |
| Image 3 Alt Text | Human CD40/TNFRSF5 Immunoprecipitation(IP) 40617 |
| Image 3 URL | Source image |
Background Information
| Full Name | CD40 molecule, TNF receptor superfamily member 5 |
| Description | CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 protein is expressed in B cells, dendritic cells, macrophages, endothelial cells, and several tumor cell lines. Defects in CD40 result in hyper-IgM immunodeficiency type 3 (HIGM3). In addition, CD40/CD40L interaction is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. |
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