Human B7-H3 ELISA Kit sinobiological KIT11188
$400.00
In stock
SKU
KIT11188
| Catalog No. | Size | Price (USD) |
| KIT11188-1 | 1 Kit (96 Tests) | $414.71 |
General Information
| Product name | Human B7-H3 ELISA Kit |
| Specificity | This assay recognizes both recombinant and natural Human B7H3. |
| Conjugate | HRP |
| Shipping | This ELISA Kit is shipped at ambient temperature. |
| Storage | Unopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA |
| Assay type | Solid Phase Sandwich ELISA (quantitative) |
| Sample type | Serum,Urine |
| Sensitivity | 7.78 pg/mL |
| Assay range | 23.44-1500 pg/mL |
| Materials provided | 1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution |
| Product overview | This Human B7-H3 ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Human B7-H3 protein in Serum,Urine . It contains recombinant Human B7-H3, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use. |
| Interference | Preparations of human B7-1, B7-2 and PD-L2 at 50 ng/mL in a mid-range recombinant human B7H3 control were assayed for interference. No significant interference was observed. |
Synonyms: B7-H3 ELISA Kit, Human; B7H3 ELISA Kit, Human; B7RP-2 ELISA Kit, Human; PSEC0249 ELISA Kit, Human; UNQ309/PRO352 ELISA Kit, Human
Image / Experimental Information
| Image 1 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 1 Alt Text | Human B7-H3/CD276 ELISA Kit Standard Curve 14508 |
| Image 1 URL | Source image |
| Image 2 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 2 Alt Text | Human B7-H3/CD276 ELISA Kit Specificity 14524 |
| Image 2 URL | Source image |
Background Information
| Full Name | CD276 molecule |
| Description | B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to either promote or inhibit T-cell responses in various experimental systems. B7-H3 may play an important role in muscle-immune interactions, providing further evidence of the active role of muscle cells in local immunoregulatory processes. B7-H3 is a novel protein structurally related to the B7 family of ligands by the presence of a single set of immunoglobulin-V-like and immunoglobulin-C-like (VC) domains. Previous studies have correlated its overexpression with poor prognosis and decreased tumor-infiltrating lymphocytes in various carcinomas including uterine endometrioid carcinomas, and mounting evidence supports an immuno-inhibitory role in ovarian cancer prognosis. Recently, B7-H3 expression has been reported in several human cancers indicating an additional function of B7-H3 as a regulator of antitumor immunity. |
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