Human BCAM ELISA Kit sinobiological KIT10238
$400.00
In stock
SKU
KIT10238
| Catalog No. | Size | Price (USD) |
| KIT10238-1 | 1 Kit (96 Tests) | $414.71 |
General Information
| Product name | Human BCAM ELISA Kit |
| Specificity | This assay recognizes both recombinant and natural Human BCAM. |
| Conjugate | HRP |
| Shipping | This ELISA Kit is shipped at ambient temperature. |
| Storage | Unopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA |
| Assay type | Solid Phase Sandwich ELISA (quantitative) |
| Sample type | Serum |
| Sensitivity | 17.7 pg/mL |
| Assay range | 39-2500 pg/mL |
| Materials provided | 1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution |
| Product overview | This Human BCAM ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Human BCAM protein in Serum . It contains recombinant Human BCAM, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use. |
Synonyms: AU ELISA Kit, Human; B-CAM ELISA Kit, Human; CD239 ELISA Kit, Human; F8/G253 ELISA Kit, Human; LU ELISA Kit, Human; MSK19 ELISA Kit, Human
Image / Experimental Information
| Image 1 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 1 Alt Text | Human BCAM / CD239 ELISA Kit Standard Curve 52 |
| Image 1 URL | Source image |
| Image 2 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 2 Alt Text | Human BCAM / CD239 ELISA Kit Specificity 251 |
| Image 2 URL | Source image |
Background Information
| Full Name | basal cell adhesion molecule (Lutheran blood group) |
| Description | The Lutheran (Lu) blood group and basal cell adhesion molecule (BCAM) antigens are both carried by 2 glycoprotein isoforms of the immunoglobulin superfamily representing receptors for the laminin alpha(5) chain. It is a transmembrane receptor with five immunoglobulin-like domains in its extracellular region, and is therefore classified as a member of the immunoglobulin (Ig) gene family. In addition to red blood cells, Lu/BCAM proteins are expressed in endothelial cells of vascular capillaries and in epithelial cells of several tissues. BCAM/LU has a wide tissue distribution with a predominant expression in the basal layer of the epithelium and the endothelium of blood vessel walls. As designated as CD239 recently, BCAM and LU share a significant sequence similarity with the CD146 (MUC18) and CD166, and themselves are adhesion molecules that bind laminin with high affinity. Laminins are found in all basement membranes and are involved in cell differentiation, adhesion, migration, and proliferation. BCAM is upregulated following malignant transformation of some cell types in vivo and in vitro, thus being a candidate molecule involved in tumor progression. In addition, BCAM interacts with integrin in sickle red cells, and thus may potentially play a role in vaso-occlusive episodes. |
| References |
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