Human CD82 ELISA Kit sinobiological KIT12275
$714.00
In stock
SKU
KIT12275
| Catalog No. | Size | Price (USD) |
| KIT12275-1 | 1 Kit (96 Tests) | $740.55 |
General Information
| Product name | Human CD82 ELISA Kit |
| Specificity | This assay recognizes recombinant Human CD82. |
| Conjugate | HRP |
| Shipping | This ELISA Kit is shipped at ambient temperature. |
| Storage | Unopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA |
| Assay type | Solid Phase Sandwich ELISA (quantitative) |
| Sample type | Recombinant protein |
| Sensitivity | 32.69 pg/mL |
| Assay range | 125-8000 pg/mL |
| Materials provided | 1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution |
| Product overview | This Human CD82 ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Human CD82 protein in Recombinant protein . It contains recombinant Human CD82, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use. |
Synonyms: 4F9 ELISA Kit, Human; C33 ELISA Kit, Human; GR15 ELISA Kit, Human; IA4 ELISA Kit, Human; KAI1 ELISA Kit, Human; R2 ELISA Kit, Human; SAR2 ELISA Kit, Human; ST6 ELISA Kit, Human; TSPAN27 ELISA Kit, Human
Image / Experimental Information
| Image 1 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 1 Alt Text | Human CD82/KAI-1 ELISA Kit Standard Curve 14509 |
| Image 1 URL | Source image |
| Image 2 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 2 Alt Text | Human CD82/KAI-1 ELISA Kit Specificity 14525 |
| Image 2 URL | Source image |
Background Information
| Full Name | CD82 molecule |
| Description | CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signalling. Downregulation of CD82 expression is associated with the advanced stages of many human cancers and correlates with the acquisition of metastatic potential. Recent studies suggest that complex mechanisms underlie CD82 loss of function, including altered transcriptional regulation, splice variant production and post-translational protein modifications, and indicate a central role for CD82 in controlling metastasis as a 'molecular facilitator'. The loss of KAI1/CD82 expression in invasive and metastatic cancers is due to a complex, epigenetic mechanism that probably involves transcription factors such as NFkappaB, p53, and beta-catenin. A loss of KAI1 expression is also associated with the advanced stages of many human malignancies and results in the acquisition of invasive and metastatic capabilities by tumour cells. Thus, KAI1/CD82 is regarded as a wide-spectrum tumor metastasis suppressor. |
| References |
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