Human Ephrin-A1 ELISA Kit sinobiological KIT10882

$714.00
In stock
SKU
KIT10882
Catalog No.SizePrice (USD)
KIT10882-11 Kit (96 Tests)$740.55

General Information

Product nameHuman Ephrin-A1 ELISA Kit
SpecificityThis assay recognizes both recombinant and natural Human EFNA1.
ConjugateHRP
ShippingThis ELISA Kit is shipped at ambient temperature.
StorageUnopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA
Assay typeSolid Phase Sandwich ELISA (quantitative)
Sample typeCell supernatant
Sensitivity9.7 pg/mL
Assay range23.44-1500 pg/mL
Materials provided1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution
Product overviewThis Human Ephrin-A1 ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Human Ephrin-A1 protein in Cell supernatant . It contains recombinant Human Ephrin-A1, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use.
InterferencePreparations of EphA2、EphA3、EphA4 and EphA7 at 15 ng/mL in a mid-range recombinant human EFNA1 control were assayed for interference. No significant interference was observed.

Synonyms: B61 ELISA Kit, Human; ECKLG ELISA Kit, Human; EFL1 ELISA Kit, Human; EPLG1 ELISA Kit, Human; GMAN ELISA Kit, Human; LERK-1 ELISA Kit, Human; LERK1 ELISA Kit, Human; TNFAIP4 ELISA Kit, Human

Image / Experimental Information

Image 1 DescriptionThis standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Image 1 Alt TextHuman Ephrin-A1/EFNA1 ELISA Kit Standard Curve 85
Image 1 URLSource image
Image 2 DescriptionThis standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Image 2 Alt TextHuman Ephrin-A1/EFNA1 ELISA Kit Specificity 228
Image 2 URLSource image

Background Information

Full Nameephrin-A1
DescriptionEPH-related receptor tyrosine kinase ligand 1 (abbreviated as Ephrin-A1) also known as ligand of eph-related kinase 1 or EFNA1, is a member of the ephrin (EPH) family. The Eph family receptor interacting proteins (ephrins) are a family of proteins that serve as the ligands of the Eph receptor, which compose the largest known subfamily of receptor protein-tyrosine kinases (RTKs). Ephrin-A1/EFNA1 and its Eph family of receptor tyrosine kinases are expressed by cells of the SVZ. Ephrin subclasses are further distinguished by their mode of attachment to the plasma membrane: ephrin-A ligands bind EphA receptors and are anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) linkage, whereas ephrin-B ligands bind EphB receptors and are anchored via a transmembrane domain. An exception is the EphA4 receptor, which binds both subclasses of ephrins. Ephrin-A1 and one of its receptor EphA2 were expressed in xenograft endothelial cells and also tumor cells and play a role in human cancers, at least in part by influencing tumor neovascularization.
References
  1. Deroanne C, et al. (2003) EphrinA1 inactivates integrin-mediated vascular smooth muscle cell spreading via the Rac/PAK pathway. J Cell Sci. 116(7): 1367-76.
  2. Ojima T, et al. (2006) EphrinA1 inhibits vascular endothelial growth factor-induced intracellular signaling and suppresses retinal neovascularization and blood-retinal barrier breakdown. Am J Pathol. 168(1): 331-9.
  3. Wu D, et al. (2004) Prognostic value of EphA2 and EphrinA-1 in squamous cell cervical carcinoma. Gynecol Oncol. 94(2): 312-9.

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