Human Her2/ERBB2 ELISA Kit sinobiological KIT10004
$400.00
In stock
SKU
KIT10004
| Catalog No. | Size | Price (USD) |
| KIT10004-1 | 1 Kit (96 Tests) | $414.71 |
General Information
| Product name | Human Her2/ERBB2 ELISA Kit |
| Specificity | This assay recognizes both recombinant and natural Human ErbB2. |
| Conjugate | HRP |
| Shipping | This ELISA Kit is shipped at ambient temperature. |
| Storage | Unopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA |
| Assay type | Solid Phase Sandwich ELISA (quantitative) |
| Sample type | Serum |
| Sensitivity | 2.47 pg/mL |
| Assay range | 23.4-1500 pg/mL |
| Materials provided | 1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution |
| Product overview | This Human Her2/ERBB2 ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Human Her2/ERBB2 protein in Serum . It contains recombinant Human Her2/ERBB2, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use. |
Synonyms: c-ERB-2 ELISA Kit, Human; c-ERB2 ELISA Kit, Human; CD340 ELISA Kit, Human; HER-2 ELISA Kit, Human; HER-2/neu ELISA Kit, Human; HER2 ELISA Kit, Human; MLN 19 ELISA Kit, Human; MLN-19 ELISA Kit, Human; MLN19 ELISA Kit, Human; NEU ELISA Kit, Human; NGL ELISA Kit, Human; p185(erbB2) ELISA Kit, Human; TKR1 ELISA Kit, Human; VSCN2 ELISA Kit, Human
Image / Experimental Information
| Image 1 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 1 Alt Text | Human HER2/ERBB2 ELISA Kit Standard Curve 31 |
| Image 1 URL | Source image |
| Image 2 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 2 Alt Text | Human HER2/ERBB2 ELISA Kit Specificity 223 |
| Image 2 URL | Source image |
Background Information
| Full Name | erb-b2 receptor tyrosine kinase 2 |
| Description | Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth factors due to the lacking of ligand binding domain of its own and autoinhibited constitutively. However, HER2 forms a heterodimer with other ligand-bound EGF receptor family members, therefore stabilizes ligand binding and enhances kinase-mediated activation of downstream molecules. HER2 plays a key role in development, cell proliferation and differentiation. HER2 gene has been reported to associate with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate, ovarian, lung cancers and so on. |
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| References |
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title: Enhancement of antibody-dependent cell-mediated cytotoxicity by endowing IgG with FcαRI (CD89) binding
authors: M Jack Borrok; Nadia M Luheshi; ...; Ping Tsui
journal: mAbs
date: 2015-05-13
pmid: 25970007
doi: 10.1080/19420862.2015.1047570
pmcid: 4623516
cited_by_count: 53
techniques: Affinity Column; Binding Assay; Cell Culture; Chromatography; Concentration Assay; Cytometry; Derivative Assay; Enzyme-linked Immunosorbent Assay; Expressing; Fluorescence; Generated; Imaging; Incubation; Injection; Isolation; Labeling; Microscopy; Purification; Staining; Standard Deviation
bioz_score: 90
title: Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC.
authors: Christina Battke; Romana Ruiss; ...; Reinhard Zeidler
journal: Cancer Immunology, Immunotherapy : CII
date: 2011-06-17
pmid: 21293856
doi: 10.1007/s00262-011-0979-5
cited_by_count: 119
techniques: Cytometry; Enzyme-linked Immunosorbent Assay; FACS; Flow Cytometry; Incubation; Staining; Western Blot
bioz_score: 90
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