Human IGFBP-6 ELISA Kit sinobiological KIT13026
$714.00
In stock
SKU
KIT13026
| Catalog No. | Size | Price (USD) |
| KIT13026-1 | 1 Kit (96 Tests) | $740.55 |
General Information
| Product name | Human IGFBP-6 ELISA Kit |
| Specificity | This assay recognizes both recombinant and natural Human IGFBP6. |
| Conjugate | HRP |
| Shipping | This ELISA Kit is shipped at ambient temperature. |
| Storage | Unopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA |
| Assay type | Solid Phase Sandwich ELISA (quantitative) |
| Sample type | Serum |
| Sensitivity | 3.26 pg/mL |
| Assay range | 9.38-600 pg/mL |
| Materials provided | 1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution |
| Product overview | This Human IGFBP-6 ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Human IGFBP-6 protein in Serum . It contains recombinant Human IGFBP-6, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use. |
| Interference | Preparations of the factors listed below at 50 ng/mL in a mid-range recombinant human IGFBP6 control were assayed for interference. No significant interference was observed. |
Synonyms: IBP6 ELISA Kit, Human
Image / Experimental Information
| Image 1 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 1 Alt Text | Human IGFBP6 / IBP6 ELISA Kit Standard Curve 17203 |
| Image 1 URL | Source image |
| Image 2 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 2 Alt Text | Human IGFBP6 / IBP6 ELISA Kit Specificity 17217 |
| Image 2 URL | Source image |
Background Information
| Full Name | insulin-like growth factor binding protein 6 |
| Description | Insulin-like growth factor-binding protein 6 (IGFBP6) is a 24-kDa protein that binds insulin-like growth factor 1 (IGF-1) and IGF-2 with high affinity and inhibits IGF action in vitro. The Insulin-like growth factor-binding protein also known as IGFBP serves as a carrier protein for Insulin-like growth factor 1. IGFBPs are distinct but are sharing regions with strong homology. All members of the IGFBP family bind IGF-I and IGF-II with about equal affinity. Insulin-like growth factor (IGF) binding proteins (IGFBPs) have been shown to either inhibit or enhance the action of IGF or act in an IGF-independent manner in the prostate. IGF-binding protein-4 (IGFBP-4) inhibits IGF-I action in vitro and is the most abundant IGFBP in the rodent arterial wall. IGFBP6 is directly downregulated by the beta-catenin/TCF complex in desmoid tumors, and imply a role for the IGF axis in the proliferation of desmoid tumors. There is mounting evidence that the structure of the IGFBP proteins plays a key role in the regulation of IGF bioavailability, by modulating its molecular size, capillary membrane permeability, target tissue specificity, cell membrane adherence, and IGF affinity. |
| References |
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