Human IGFBP7 ELISA Kit sinobiological KIT13100

$714.00
In stock
SKU
KIT13100
Catalog No.SizePrice (USD)
KIT13100-11 Kit (96 Tests)$740.55

General Information

Product nameHuman IGFBP7 ELISA Kit
SpecificityThis assay recognizes both recombinant and natural Human IGFBP7.
ConjugateHRP
ShippingThis ELISA Kit is shipped at ambient temperature.
StorageUnopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA
Assay typeSolid Phase Sandwich ELISA (quantitative)
Sample typeSerum
Sensitivity18.4 pg/mL
Assay range47-3000 pg/mL
Materials provided1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution
Product overviewThis Human IGFBP7 ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Human IGFBP7 protein in Serum . It contains recombinant Human IGFBP7, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use.

Synonyms: AGM ELISA Kit, Human; FSTL2 ELISA Kit, Human; IBP-7 ELISA Kit, Human; IGFBP-7 ELISA Kit, Human; IGFBP-7v ELISA Kit, Human; IGFBPRP1 ELISA Kit, Human; MAC25 ELISA Kit, Human; PSF ELISA Kit, Human; RAMSVPS ELISA Kit, Human; TAF ELISA Kit, Human

Image / Experimental Information

Image 1 DescriptionThis standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Image 1 Alt TextHuman IGFBP7 ELISA Kit Standard Curve 117
Image 1 URLSource image
Image 2 DescriptionThis standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Image 2 Alt TextHuman IGFBP7 ELISA Kit Specificity 218
Image 2 URLSource image

Background Information

Full Nameinsulin-like growth factor binding protein 7
DescriptionInsulin-like growth factor-binding protein 7 (IGFBP7) is a member of the IGFBP family. It has been identified in colorectal adenocarcinoma (CRC) cell lines. The Insulin-like growth factor-binding protein also known as IGFBP serves as a carrier protein for Insulin-like growth factor 1. IGFBPs are distinct but are sharing regions with strong homology. All members of the IGFBP family bind IGF-I and IGF-II with about equal affinity. Insulin-like growth factor (IGF) binding proteins (IGFBPs) have been shown to either inhibit or enhance the action of IGF or act in an IGF-independent manner in the prostate. IGFBP7 could inhibit cell growth, decrease soft agar colony formation activity, and induce apoptosis in RKO and SW620 cells. There is mounting evidence that the structure of the IGFBP proteins plays a key role in the regulation of IGF bioavailability, by modulating its molecular size, capillary membrane permeability, target tissue specificity, cell membrane adherence, and IGF affinity.
References
  1. Oh Y, et al. (1996) Synthesis and characterization of insulin-like growth factor-binding protein (IGFBP)-7. Recombinant human mac25 protein specifically binds IGF-I and -II. J Biol Chem. 271(48): 30322-5.
  2. Wilson EM, et al. (1997) Generation and characterization of an IGFBP-7 antibody: identification of 31kD IGFBP-7 in human biological fluids and Hs578T human breast cancer conditioned media. J Clin Endocrinol Metab. 82(4): 1301-3.
  3. Lin J, et al. (2007) Methylation patterns of IGFBP7 in colon cancer cell lines are associated with levels of gene expression. J Pathol. 212(1): 83-90.

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