Human PDGF alpha receptor/PDGFRA ELISA Kit sinobiological KIT10556
$714.00
In stock
SKU
KIT10556
| Catalog No. | Size | Price (USD) |
| KIT10556-1 | 1 Kit (96 Tests) | $740.55 |
General Information
| Product name | Human PDGF alpha receptor/PDGFRA ELISA Kit |
| Specificity | This assay recognizes both recombinant and natural Human PDGFRA. |
| Conjugate | HRP |
| Shipping | This ELISA Kit is shipped at ambient temperature. |
| Storage | Unopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA |
| Assay type | Solid Phase Sandwich ELISA (quantitative) |
| Sample type | Serum |
| Sensitivity | 86.73 pg/mL |
| Assay range | 109.38-7000 pg/mL |
| Materials provided | 1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution |
| Product overview | This Human PDGF alpha receptor/PDGFRA ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Human PDGF alpha receptor/PDGFRA protein in Serum . It contains recombinant Human PDGF alpha receptor/PDGFRA, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use. |
Synonyms: CD140A ELISA Kit, Human; GAS9 ELISA Kit, Human; PDGFR-2 ELISA Kit, Human; PDGFR2 ELISA Kit, Human; RHEPDGFRA ELISA Kit, Human
Image / Experimental Information
| Image 1 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 1 Alt Text | Human PDGFRA/CD140a ELISA Kit Standard Curve 17211 |
| Image 1 URL | Source image |
| Image 2 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 2 Alt Text | Human PDGFRA/CD140a ELISA Kit Specificity 17225 |
| Image 2 URL | Source image |
Background Information
| Full Name | platelet-derived growth factor receptor, alpha polypeptide |
| Description | PDGFRA, also known as CD140a, together with the structurally homolog protein PDGFRB (CD140b), are cell surface receptors for members of the platelet-derived growth factor family. They are members of the class III subfamily of receptor tyrosine kinase (RTKs) with the similar structure characteristics of five immunoglobulin-like domains in their extracellular region and a split kinase domain in their intracellular region. PDGFRA is expressed in oligodendrocyte progenitor cells and mesothelial cell, and binds all three ligand isoforms PDGF-AA, PDGF-BB and PDGF-AB with high affinity, whereas PDGFRB dose not bind PDGF-AA. PDGFRA plays an essential role in regulating proliferation, chemotaxis and migration of mesangial cells. Recent studies have indicated that PDGFRA acts as a critical mediator of signaling in testis organogenesis and Leydig cell differentiation, and in addition, particularly important for kidney development. Additionally, PDGFRA is involved in tumor angiogenesis and maintenance of the tumor microenvironment and has been implicated in development and metastasis of Hepatocellular carcinoma (HCC). PDGFRA may represent a potential therapeutic target in thymic tumours. PDGFRA gene amplification rather than gene mutation may be the underlying genetic mechanism driving PDGFRA overexpression in a portion of gliomas. |
| Research Areas |
|
| Tags |
|
| References |
|
Reviews
Write Your Own Review
Related Products
Check items to add to the cart or
