Human uPAR/PLAUR ELISA Kit sinobiological KIT10925
$400.00
In stock
SKU
KIT10925
| Catalog No. | Size | Price (USD) |
| KIT10925-1 | 1 KIT (96 Tests) | $414.71 |
General Information
| Product name | Human uPAR/PLAUR ELISA Kit |
| Specificity | This assay recognizes both recombinant and natural Human UPAR. |
| Conjugate | HRP |
| Shipping | This ELISA Kit is shipped at ambient temperature. |
| Storage | Unopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA |
| Assay type | Solid Phase Sandwich ELISA (quantitative) |
| Sample type | Serum |
| Sensitivity | 0.12 pg/mL |
| Assay range | 4.69-300 pg/mL |
| Materials provided | 1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution |
| Product overview | This Human uPAR/PLAUR ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Human uPAR/PLAUR protein in Serum . It contains recombinant Human uPAR/PLAUR, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use. |
Synonyms: CD87 ELISA Kit, Human; MO3 ELISA Kit, Human; U-PAR ELISA Kit, Human; UPAR ELISA Kit, Human; URKR ELISA Kit, Human
Image / Experimental Information
| Image 1 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 1 Alt Text | Human PLAUR/CD87 ELISA Kit Standard Curve 16 |
| Image 1 URL | Source image |
| Image 2 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 2 Alt Text | Human PLAUR/CD87 ELISA Kit Specificity 191 |
| Image 2 URL | Source image |
Background Information
| Full Name | plasminogen activator, urokinase receptor |
| Description | Urokinase plasminogen activator (uPA) and/or its receptor (uPAR) are essential for metastasis, and overexpression of these molecules is strongly correlated with poor prognosis in a variety of malignant tumours. uPAR and uPA levels in both resected tumor tissue and plasma are of independent prognostic significance for patient survival in several types of human cancer. This system has classically been thought to drive tumor progression by mediating directed extracellular proteolysis on the surface of migrating or invading cells, and intervening with this proteolysis by targeting uPAR has been proposed to represent a novel approach for inhibiting tumor progression. uPAR, also known as PLAUR or CD87, has been implicated in the growth, metastasis, and angiogenesis of several solid and hemotologic malignancies. uPAR is a highly glycosylated, 55-60kDa integral membrane protein linked to the plasma membrane by a glycosylphosphatidylinositol (GPI) anchor. It is part of a cell surface system that also consists of the serine protease uPA and several specific inhibitors (plasminogen activator inhibitors 1 and 2). Additionally, the analysis of CD87 (urokinase-type plasminogen activator receptor - uPAR) expression has a potential role in the diagnostic or prognostic work-up of several hematological malignancies, particularly acute leukemia and multiple myeloma. |
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