Anti-CD7 Antibody, Mouse Monoclonal sinobiological 11028-MM10

$143.00
In stock
SKU
11028-MM10
Catalog No.SizePrice (USD)
11028-MM10-5050 µL$147.96
11028-MM10-100100 µL$251.64
11028-MM10-200200 µL$355.32

General Information

Product nameAnti-CD7 Antibody, Mouse Monoclonal
Validated applicationsWB (FAQ Protocol), ELISA (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman CD7
ImmunogenRecombinant Human CD7 Protein (Catalog#11028-H08H)
PreparationThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD7 (rh CD7; Catalog#11028-H08H; NP_006128.1; Met1-Pro180). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
SourceMonoclonal Mouse IgG1 Clone #10
PurificationProtein A
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-GP40 Antibody; Anti-LEU-9 Antibody; Anti-Tp40 Antibody; Anti-TP41 Antibody

Image / Experimental Information

Image 1 DescriptionAnti-CD7 mouse monoclonal antibody at 1:500 dilution Lane A: Jurkat Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Mouse IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:25 kDa Observed band size:37 kDa
Image 1 Alt TextHuman CD7 Western blot (WB) 22265
Image 1 URLSource image

Background Information

Full NameCD7 molecule
DescriptionThe cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD7 is a transmembrane protein that is a member of the immunoglobulin superfamily. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell / B-cell interaction during early lymphoid development.
References
  1. Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
  2. Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
  3. Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.

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