Kinase Inhibitors: Y-27632 2HCl sinobiological R10-900B
$100.00
In stock
SKU
R10-900B
| Catalog No. | Size | Price (USD) |
| R10-900B-5 | 5 mg | $103.68 |
| R10-900B-25 | 25 mg | $303.63 |
General Information
| Purity | 99% (HPLC); NMR (Conforms) |
| Molecule Mass | 320.3 |
| Detail | ROCK inhibitor. For specific information on a given lot, see related technical data sheet. |
| Aliases | (R)-(+)-trans-4-(1-Aminoethyl)-N-(-4-pyridyl) cyclohexanecarboxamide dihydrochloride |
| CAS Registry Number | 129830-38-2 |
| Molecular Formula | C 14 H 21 N 3 O 2 HCl |
| Appearance | White to off-white powder |
| Solubilization | May be dissolved in DMSO (25 mg/mL) |
| Storage and Stability | Store desiccated as supplied at ambient temperature for up to 2 years. Store solutions at -20°C for up to 3 months. |
| Research Areas | Apoptosis/Autophagy, Cancer, Cardiovascular Disease, Inflammation, Invasion/Metastasis, Ser/Thr Kinases |
Background Information
| Description | Specific inhibitor of ROCK family kinases (1). Enhances stem cell survival and proliferation in culture (2). Significantly improves freeze/thaw survival rate for human embryonic stem cells without influencing morphology, karyotype, cell surface markers or differentiation potential (3). |
title: Comparative analysis of porcine iPSCs derived from Sertoli cells and fibroblasts.
authors: Shuai Yu; Zhenshuo Zhu; ...; Jinlian Hua
journal: Journal of Cellular Physiology
date: 2022-12-20
pmid: 36288570
doi: 10.1002/jcp.30903
cited_by_count: 1
techniques: In Vitro
bioz_score: 90
title: Development of an innervated tissue-engineered skin with human sensory neurons and Schwann cells differentiated from iPS cells.
authors: Quentin Muller; Marie-Josée Beaudet; ...; François Berthod
journal: Acta Biomaterialia
date: 2019-07-11
pmid: 30316025
doi: 10.1016/j.actbio.2018.10.011
cited_by_count: 69
techniques: Cell Culture; Enzyme-linked Immunosorbent Assay
bioz_score: 90
title: Ap4 is rate limiting for intestinal tumor formation by controlling the homeostasis of intestinal stem cells
authors: Stephanie Jaeckel; Markus Kaller; ...; Heiko Hermeking
journal: Nature Communications
date: 2018-09-03
pmid: 30177706
doi: 10.1038/s41467-018-06001-x
pmcid: 6120921
cited_by_count: 15
techniques: Isolation; Modification; Passaging
bioz_score: 90
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