Anti-CD7 Antibody (PE), Mouse Monoclonal sinobiological 11028-MM20-P

$100.00
In stock
SKU
11028-MM20-P
Catalog No.SizePrice (USD)
11028-MM20-P-2525 Tests$103.68
11028-MM20-P-100100 Tests$222.17

General Information

Product nameAnti-CD7 Antibody (PE), Mouse Monoclonal
Validated applicationsFCM (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman CD7
ImmunogenHuman CD7 Plasmid
PreparationThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with Human CD7 Plasmid. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
SourceMonoclonal Mouse IgG2b Clone #20
PurificationProtein A
FormulationPBS solution containing 0.5% BSA and 0.03%ProClin300
Concentration2 μl/Test, 0.1 mg/ml
ConjugatePE
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze !

Synonyms: Anti-GP40 Antibody; Anti-LEU-9 Antibody; Anti-Tp40 Antibody; Anti-TP41 Antibody

Image / Experimental Information

Image 1 DescriptionFlow cytometric analysis of Human CD7 expression on human whole blood Lymphocytes. Cells were stained with PE-conjugated anti-Human CD7. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable Lymphocytes.
Image 1 Alt TextHuman CD7 Flow Cytometry (FC) 21114
Image 1 URLSource image

Background Information

Full NameCD7 molecule
DescriptionThe cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD7 is a transmembrane protein that is a member of the immunoglobulin superfamily. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell / B-cell interaction during early lymphoid development.
References
  1. Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
  2. Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
  3. Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.

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