Anti-CD81 Antibody (HRP), Mouse Monoclonal sinobiological 14244-MM01-H

$343.00
In stock
SKU
14244-MM01-H
Catalog No.SizePrice (USD)
14244-MM01-H-100100 µg$355.47

General Information

Product nameAnti-CD81 Antibody (HRP), Mouse Monoclonal
Validated applicationsELISA (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman CD81
ImmunogenRecombinant Human CD81 Protein (Catalog#14244-HNCH)
PreparationThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD81 (rh CD81; Catalog#14244-HNCH; NP_004347.1; Phe113-Lys201). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography and conjugated with horseradish-peroxidase (HRP).
SourceMonoclonal Mouse IgG1 Clone #01
PurificationProtein A
Formulation0.2 μm filtered solution in PBS
ConjugateHRP
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Protected from prolonged exposure to light. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-CVID6 Antibody; Anti-S5.7 Antibody; Anti-TAPA-1 Antibody; Anti-TAPA1 Antibody; Anti-TSPAN28 Antibody

Background Information

Full NameCD81 molecule
DescriptionCD81, also known as TAPA-1, belongs to the transmembrane 4 superfamily, also known as the tetraspanin family. Members of this family mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.CD81 is a widely expressed cell-surface protein involved in an astonishing variety of biologic responses. It is related to adhesion, morphology, activation, proliferation, and differentiation of B, T, and other cells. On B cells CD81 is part of a complex with CD21, CD19, and Leu13. This complex reduces the threshold for B cell activation via the B cell receptor by bridging Ag specific recognition and CD21-mediated complement recognition.
References
  1. Petracca R. et al., 2000, J Virol. 74 (10): 4824-30.
  2. Bartosch B. et al., 2003, The Journal of Biological Chemistry. 278 (43): 41624-30.
  3. Clark KL. et al., 2001, Journal of Immunology. 167 (9): 5115-21.

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