| Catalog No. | Size | Price (USD) |
| 11763-MM02-P-25 | 25 Tests | $133.30 |
| 11763-MM02-P-100 | 100 Tests | $325.84 |
General Information
| Product name | Anti-CD83 Antibody (PE), Mouse Monoclonal |
| Validated applications | FCM (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human CD83 |
| Immunogen | Recombinant Human CD83 Protein (Catalog#11763-H08H) |
| Preparation | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD83 (rh CD83; Catalog#11763-H08H; Q01151-1; Met1-Ala143) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| Source | Monoclonal Mouse IgG2b Clone #02 |
| Purification | Protein A |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Concentration | 10 μl/Test, 0.1 mg/ml |
| Conjugate | PE |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
Synonyms: Anti-BL11 Antibody; Anti-HB15 Antibody
Image / Experimental Information
| Image 1 Description | Flow cytometric analysis of Human CD83 expression on DC. Cells were stained with PE-conjugated anti-Human CD83. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Image 1 Alt Text | Human CD83 Flow Cytometry (FC) 27432 |
| Image 1 URL | Source image |
Background Information
| Full Name | CD83 molecule |
| Description | The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD83 is considered as a marker of mature dendritic cells as well as an adhesion receptor that binds to resting monocytes and a subset of activated CD8 T cells. In certain conditions, CD83 tended to dimerize or even multimerize through its aberrant intermolecular disulfide bonds. The injection of CD83 Ig can significantly enhance the rate of tumor growth and inhibit the T cell growth. |
| References |
|
