Anti-B7-2/CD86 Antibody, Rabbit Polyclonal sinobiological 10699-T50
$243.00
In stock
SKU
10699-T50
| Catalog No. | Size | Price (USD) |
| 10699-T50-100 | 100 µL | $251.64 |
General Information
| Product name | Anti-B7-2/CD86 Antibody, Rabbit Polyclonal |
| Validated applications | WB (FAQ Protocol), ELISA (FAQ Protocol), ICC/IF (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human B7-2/CD86 |
| Immunogen | Recombinant Human CD86 Protein (Catalog#10699-H08H) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human CD86 (rh CD86; Catalog#10699-H08H; NP_008820.2; Met1-His239). CD86 specific IgG was purified by Human CD86 affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-B7-2 Antibody; Anti-B7.2 Antibody; Anti-B70 Antibody; Anti-CD28LG2 Antibody; Anti-LAB72 Antibody
Image / Experimental Information
| Image 1 Description | Anti-B7-2 rabbit polyclonal antibody at 1:500 dilution Lane A: Raji Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size: 70 kDa Observed band size: 75 kDa |
| Image 1 Alt Text | Human CD86 Western blot (WB) 37607 |
| Image 1 URL | Source image |
| Image 2 Description | Anti-B7-2 rabbit polyclonal antibody at 1:500 dilution Lane A: Raji Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size: 70 kDa Observed band size: 75 kDa |
| Image 2 Alt Text | Human CD86 Immunofluorescence(IF) 37608 |
| Image 2 URL | Source image |
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Background Information
| Full Name | CD86 antigen |
| Description | CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co-stimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells, and thus induces the signal pathways which regulate T cell activation and tolerance, cytokine production, and the generation of CTL. It is indicated that contacts between B and T helper cells mediated by CD86 encourage signals for the proliferation and IgG secretion of normal B cells and B cell lymphomas. A recent study has revealed that CD86 also promotes the generation of a mature APC repertoire and promotes APC function and survival. CD86 has an important role in chronic hemodialysis, allergic pulmonary inflammation, arthritis, and antiviral responses, and thus is regarded as a promising candidate for immune therapy. |
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