Anti-CDC42 Antibody, Rabbit Polyclonal sinobiological 109866-T36

$143.00
In stock
SKU
109866-T36
Catalog No.SizePrice (USD)
109866-T36-5050 µL$147.96
109866-T36-100100 µL$251.64
109866-T36-200200 µL$355.32

General Information

Product nameAnti-CDC42 Antibody, Rabbit Polyclonal
Validated applicationsWB (FAQ Protocol), IP (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman CDC42
ImmunogenA synthetic peptide corresponding to the center region of the Human CDC42
PreparationProduced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human CDC42, and purified by antigen affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A & Antigen Affinity
FormulationPBS, pH7.0 with 0.03% Proclin300
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-CDC42Hs Antibody; Anti-G25K Antibody; Anti-TKS Antibody

Image / Experimental Information

Image 1 DescriptionAnti-CDC42 rabbit polyclonal antibody at 1:500 dilution Lane A: HeLa Whole Cell Lysate Lane B: HepG2 Whole Cell Lysate Lane C: 293T Whole Cell Lysate Lane D: Jurkat Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:21 kDa Observed band size:21 kDa
Image 1 Alt TextHuman CDC42 Western blot (WB) 34980
Image 1 URLSource image
Image 2 DescriptionAnti-CDC42 rabbit polyclonal antibody at 1:500 dilution Lane A: HeLa Whole Cell Lysate Lane B: HepG2 Whole Cell Lysate Lane C: 293T Whole Cell Lysate Lane D: Jurkat Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:21 kDa Observed band size:21 kDa
Image 2 Alt TextHuman CDC42 Immunoprecipitation(IP) 34981
Image 2 URLSource image

Background Information

Full Namecell division cycle 42
Related Pathways
  • Non-Canonical Wnt Pathway
  • TGF-beta Signaling
  • Actin Dynamics Signaling Pathway
  • B Cell Receptor Signaling Pathway
  • T Cell Receptor Signaling Pathway
References
  1. Shinjo K, et al. (1990) Molecular cloning of the gene for the human placental GTP-binding protein Gp (G25K): identification of this GTP-binding protein as the human homolog of the yeast cell-division-cycle protein CDC42. Proc Natl Acad Sci. 87(24):9853-7.
  2. Munemitsu S, et al. (1990) Molecular cloning and expression of a G25K cDNA, the human homolog of the yeast cell cycle gene CDC42. Mol Cell Biol. 10(11):5977-82.
  3. Walker S J, et al. (2000) Activation of phospholipase D1 by Cdc42 requires the Rho insert region. J Biol Chem. 275(21):15665-8.
  4. Low B C, et al. (1999) Tyrosine phosphorylation of the Bcl-2-associated protein BNIP-2 by fibroblast growth factor receptor-1 prevents its binding to Cdc42GAP and Cdc42. J Biol Chem. 274(46): 33123-30.
  5. Zhang B, et al. (1998) Interaction of Rac1 with GTPase-activating proteins and putative effectors. A comparison with Cdc42 and RhoA. J Biol Chem. 273(15):8776-82.

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