| Catalog No. | Size | Price (USD) |
| 11821-HNAE-1 | 1 mg | $3,833.11 |
| 11821-HNAE-10 | 10 µg | $189.58 |
| 11821-HNAE-20 | 20 µg | $308.07 |
| 11821-HNAE-100 | 100 µg | $737.59 |
General Information
| Formulation | Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Endotoxin | < 0.01 EU per μg of the protein. |
| Shipping | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
| Stability & Storage | Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Reconstitution | To find reconstitution info, click on 'COA' at the top of the page, enter the lot number and product size for the lot-specific COA. |
| Purity | ≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC. |
| Activity | Measured in a cell proliferation assay using anti-CD3 antibody activated human peripheral blood mononuclear cell (PBMC). The ED 50 for this effect is typically 0.5-8 ng/ml. |
| Protein Construction | A DNA sequence encoding the mature form of human IL7 (NP_000871.1)(Asp26-His177) was expressed with a N-terminal Met. |
| Accession# | NP_000871.1 |
| Expressed Host | E. coli |
| Species | Human |
| Predicted N Terminal | Met |
| Molecule Mass | The recombinant human IL7 consists of 153 amino acids and predicts a molecular mass of 17.5 KDa. It migrates as an approximately 20.4 KDa band in SDS-PAGE under reducing conditions. |
Synonyms: IL-7 Protein, Human
Image / Experimental Information
| Image 1 Alt Text | Human IL7/IL-7/Interleukin-7 Protein 9841 |
| Image 1 URL | Source image |
| Image 2 Alt Text | Human IL-7 Protein 33203 |
| Image 2 URL | Source image |
| Image 3 Alt Text | Human IL-7 Protein 34167 |
| Image 3 URL | Source image |
Background Information
| Full Name | interleukin 7 |
| Description | IL7, also known as interleukin 7, is a hematopoietic growth factor that belongs to the IL-7/IL-9 family. It is secreted by stromal cells in the bone marrow and thymus. IL7 stimulates the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. IL7 and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. It is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRß) during early T cell development. IL7 can be produced locally by intestinal epithelial and epithelial goblet cells and may serve as a regulatory factor for intestinal mucosal lymphocytes. |
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| References |
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title: Engineered human iPSC-derived dendritic cells dressed with tumor MHC complexes as a cancer vaccine.
authors: Huaigeng Xu; Chisato Kamei; ...; Robert Blelloch
journal: Cell Stem Cell
date: 2026-08-25
pmid: 42641609
doi: 10.1016/j.stem.2026.07.017
cited_by_count: 0
techniques: Activation Assay; Blocking Assay; Cell Fractionation; Cell Isolation; Clinical Proteomics; Disruption; Filtration; Isolation; Membrane; Recombinant; Red Blood Cell Lysis; Selection
bioz_score: 94
title: Droplet single-cell CRISPR screens identify regulators of T cell–mediated target-cell killing
authors: Saronio Giulia; Antonini Gaia; ...; Geiger Roger
journal: bioRxiv
date: 2026-06-29
doi: 10.64898/2026.06.23.734054
cited_by_count: 0
techniques: Cell Culture; Centrifugation; Expressing; Isolation; Purification; Recombinant
bioz_score: 94
title: Microparticle-enabled single cell multiparameter electronic immunophenotyping for selective electroporation
authors: Madeline Hoyle; Josiah Rudge; ...; Aniruddh Sarkar
journal: Lab on a Chip
date: 2026-05-05
pmid: 41966093
cited_by_count: 0
techniques: Cell Culture; Isolation
bioz_score: 94
title: Discovery of a new anti-γc antibody in clinical development for the treatment of autoimmune diseases
authors: Chin Wai Hui; Wai Chung Wu; ...; Shui On Leung
journal: The Journal of Immunology
date: 2025-03-12
doi: 10.1093/jimmun/vkae020
cited_by_count: 0
techniques: Control; Recombinant
bioz_score: 93
title: Alarmin-loaded extracellular lipid droplets induce airway neutrophil infiltration during type 2 inflammation.
authors: Zebing Rao; Shaorui Liu; ...; Heping Xu
journal: Immunity
date: 2024-11-13
pmid: 39366382
doi: 10.1016/j.immuni.2024.09.001
cited_by_count: 14
techniques: Recombinant
bioz_score: 93
title: Heterologous survey of 130 DNA transposons in human cells highlights their functional divergence and expands the genome engineering toolbox.
authors: Tongtong Zhang; Shengjun Tan; ...; Yong E Zhang
journal: Cell
date: 2024-07-12
pmid: 38843831
doi: 10.1016/j.cell.2024.05.007
cited_by_count: 10
techniques: Construct; Recombinant
bioz_score: 93
title: Suppression of NK Cell Activation by JAK3 Inhibition: Implication in the Treatment of Autoimmune Diseases
authors: Wai Chung Wu; Carol Shiu; ...; Chin Wai Hui
journal: Journal of immunology research
date: 2023-01-01
pmid: 38106519
doi: 10.1155/2023/8924603
pmcid: 10723930
cited_by_count: 4
bioz_score: 93
title: Interleukins 4 and 21 Protect Anti-IgM Induced Cell Death in Ramos B Cells: Implication for Autoimmune Diseases.
authors: Chin Wai Hui; Wai Chung Wu; Shui On Leung
journal: Frontiers in Immunology
date: 2022-08-02
pmid: 35911775
doi: 10.3389/fimmu.2022.919854
cited_by_count: 5
techniques: Recombinant
bioz_score: 93
title: Efficient generation of locus-specific human CAR-T cells with CRISPR/cCas12a
authors: Xinyu Ling; Liying Chang; ...; Tao Liu
journal: STAR Protocols
date: 2022-04-14
pmid: 35496795
doi: 10.1016/j.xpro.2022.101321
pmcid: 9038777
cited_by_count: 11
techniques: Cytotoxicity Assay; DNA Extraction; Electroporation; Enzyme-linked Immunosorbent Assay; Flow Cytometry; Modification; Plasmid Preparation; Protein Purification; Real-time Polymerase Chain Reaction; Recombinant; SYBR Green Assay; Software; Spectrophotometry; Synthesized; Transfection
bioz_score: 93
title: Improving the efficiency of CRISPR-Cas12a-based genome editing with site-specific covalent Cas12a-crRNA conjugates.
authors: Xinyu Ling; Liying Chang; ...; Tao Liu
journal: Molecular cell
date: 2022-01-07
pmid: 34648747
doi: 10.1016/j.molcel.2021.09.021
cited_by_count: 62
techniques: Electroporation; Enzyme-linked Immunosorbent Assay; Modification; Polymerase Chain Reaction; Recombinant
bioz_score: 93
