Anti-CEACAM-3/CD66d Antibody, Rabbit Polyclonal sinobiological 11933-T16
$243.00
In stock
SKU
11933-T16
| Catalog No. | Size | Price (USD) |
| 11933-T16-100 | 100 µL | $251.64 |
General Information
| Product name | Anti-CEACAM-3/CD66d Antibody, Rabbit Polyclonal |
| Validated applications | ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human CEACAM-3/CD66d |
| Immunogen | Recombinant Human CEACAM3 Protein (Catalog#11933-H08H) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human CEACAM3 (rh CEACAM3; Catalog#11933-H08H; NP_001806.2; Met1-Gly155). CEACAM3 specific IgG was purified by Human CEACAM3 affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-CD66D Antibody; Anti-CEA Antibody; Anti-CGM1 Antibody; Anti-CGM1a Antibody; Anti-W264 Antibody; Anti-W282 Antibody
Background Information
| Full Name | carcinoembryonic antigen related cell adhesion molecule 3 |
| Description | CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66a, CD66b, CD66c, and CD66d. Members of CEACAM family are widely expressed especially on human neutrophils, and, depending on the tissue, capable of regulating diverse functions including tumor promotion, tumor suppression, angiogenesis, and neutrophil activation. Abnormal overexpression and downregulation of some CEACAMs have been described in tumor cells. Monoclonal antibodies grouped in the CD66 cluster recognize CEACAM members. Ectopic CD66 expression is commonly detected in B-cell lineage acute lymphoblastic leukemia (ALL). CEACAM3 mediates phagocytosis depends on the integrity of an ITAM-like sequence within the cytoplasmic domain of CEACAM3. CEACAM3 is characterized by rapid stimulation of the GTPase Rac. |
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| References |
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