Anti-CLINT1 Antibody, Rabbit Polyclonal sinobiological 203899-T08

$143.00
In stock
SKU
203899-T08
Catalog No.SizePrice (USD)
203899-T08-5050 µL$147.96
203899-T08-100100 µL$251.64
203899-T08-200200 µL$355.32

General Information

Product nameAnti-CLINT1 Antibody, Rabbit Polyclonal
Validated applicationsIHC-P (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman CLINT1
ImmunogenE. coli-derived Human CLINT1 fragment
PreparationProduced in rabbits immunized with E. coli-derived Human CLINT1 fragment, and purified by antigen affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A & Antigen Affinity
FormulationPBS, pH7.0 with 0.03% Proclin300
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-CLINT Antibody; Anti-ENTH Antibody; Anti-EPN4 Antibody; Anti-EPNR Antibody; Anti-KIAA0171 Antibody

Image / Experimental Information

Image 1 DescriptionImmunochemical staining of human CLINT1 in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
Image 1 Alt TextHuman CLINT1 Immunohistochemistry(IHC) 33402
Image 1 URLSource image

Background Information

DescriptionClathrin interactor 1 [CLINT1] (also called enthoprotin/EpsinR) is an Epsin N-terminal homology (ENTH) domain-containing adaptor protein that functions in anterograde and retrograde clathrin-mediated trafficking between the trans-Golgi network and the endosome. CLINT1 binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). CLINT1 may have a role in transport via clathrin-coated vesicles from the trans-Golgi network to endosomes. The CLINT1 protein binds to the terminal domain of the clathrin heavy chain and stimulates clathrin cage vesicle assembly.
References
  1. Leventis PA, et al. (2011) Liquid facets-related (lqfr) is required for egg chamber morphogenesis during drosophila oogenesis. PLoS One 6 (10): e25466.

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