| Catalog No. | Size | Price (USD) |
| 201376-T36-50 | 50 µL | $147.96 |
| 201376-T36-100 | 100 µL | $251.64 |
| 201376-T36-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-CMAS Antibody, Rabbit Polyclonal |
| Validated applications | WB (FAQ Protocol), IP (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human CMAS |
| Immunogen | E. coli-derived Human CMAS fragment |
| Preparation | Produced in rabbits immunized with E. coli-derived Human CMAS fragment, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | PBS, pH7.0 with 0.03% Proclin300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-CSS Antibody
Image / Experimental Information
| Image 1 Description | Anti-CMAS rabbit polyclonal antibody at 1:500 dilution Lane A: 293T Whole Cell Lysate Lane B: HeLa Whole Cell Lysate Lane C: U-251 MG Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:48 kDa Observed band size:48 kDa (We are unsure as to the identity of these extra bands.) |
| Image 1 Alt Text | Human CMAS Western blot (WB) 28780 |
| Image 1 URL | Source image |
| Image 2 Description | Anti-CMAS rabbit polyclonal antibody at 1:500 dilution Lane A: 293T Whole Cell Lysate Lane B: HeLa Whole Cell Lysate Lane C: U-251 MG Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:48 kDa Observed band size:48 kDa (We are unsure as to the identity of these extra bands.) |
| Image 2 Alt Text | Human CMAS Immunoprecipitation(IP) 28781 |
| Image 2 URL | Source image |
Background Information
| Description | As a component of cell surface glycoconjugates, Neu5Ac is pivotal to numerous cellular recognition and communication processes including host-parasite interactions. A prerequisite for the synthesis of sialylated glycoconjugates is the activation of Neu5Ac to cytidine-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac). Cytidine 5-prime-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac) provides the substrate required for the addition of sialic acid. CMP-sialic acid synthetase (CMAS) is one of four enzymes involved in NeuNAc metabolism, as it catalyzes the formation of CMP-NeuNAc. Cytidine monophosphate-sialic acid synthetase (CSS) catalyzes the metabolic activation of sialic acids. In vertebrates, the enzyme is chimeric, with the N-terminal domain harboring the synthetase activity. |
| References |
|
-HD12OC0833-WB.png){kind=link}
