Anti-Contactin-4 Antibody, Rabbit Polyclonal sinobiological 10178-T24
$243.00
In stock
SKU
10178-T24
| Catalog No. | Size | Price (USD) |
| 10178-T24-100 | 100 µL | $251.64 |
General Information
| Product name | Anti-Contactin-4 Antibody, Rabbit Polyclonal |
| Validated applications | ELISA (FAQ Protocol), IHC-P (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human Contactin-4 |
| Immunogen | Recombinant Human CNTN4 Protein (Catalog#10178-H08B) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human CNTN4 (rh CNTN4; Catalog#10178-H08B; Q8IWV2-1; Met1-Ser1000). CNTN4 specific IgG was purified by Human CNTN4 affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-AXCAM Antibody; Anti-BIG-2 Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining of human CNTN4 in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections. |
| Image 1 Alt Text | Human CNTN4 Immunohistochemistry(IHC) 37420 |
| Image 1 URL | Source image |
| Image 2 Description | Immunochemical staining of human CNTN4 in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections. |
| Image 2 Alt Text | Human CNTN4 Immunohistochemistry(IHC) 37421 |
| Image 2 URL | Source image |
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Background Information
| Full Name | contactin 4 |
| Description | Contactin-4, abbreviated as CNTN4, is a brain-derived protein belonging to the immunoglobulin superfamily. It has been found high expression in testes, thyroid, small intestine, uterus and brain. This protein is an neuronal membrane protein that functions as an glycosylphosphatidylinositol- anchored cell adhesion molecule. Contactin-4 is considered as a candidate protein responsible for the differentiation potential of human neuroblastoma cells and it has been implicated in some cases of autism and spinocerebellar ataxia type 16. Studies of the cantactin family have revealed a complex pattern of hemophilic and heterophilic interactions that are required for axon growth and pathfinding. Such studies demonstrate that these essential functions are mediated by the combination and juxtaposition of multiple Ig and FNIII domains. Second, these neuronal adhesion molecules demonstrate highly regulated temporal and spatial expression patterns in the CNS. For this reason, the disruption of the regulatory region of the predominant brain-expressed isoform reasonable would be expected to have significant functional consequences. |
| References |
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