Anti-COMMD8 Antibody, Rabbit Polyclonal sinobiological 201246-T44

$128.00
In stock
SKU
201246-T44
Catalog No.SizePrice (USD)
201246-T44-5050 µL$133.15
201246-T44-100100 µL$251.64
201246-T44-200200 µL$340.51

General Information

Product nameAnti-COMMD8 Antibody, Rabbit Polyclonal
Validated applicationsWB (FAQ Protocol), IHC-P (FAQ Protocol), IP (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman COMMD8
ImmunogenE. coli-derived Human COMMD8 fragment
PreparationProduced in rabbits immunized with E. coli-derived Human COMMD8 fragment, and purified by antigen affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A & Antigen Affinity
FormulationPBS, pH7.0 with 0.03% Proclin300
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-FLJ20502 Antibody; Anti-MDS022 Antibody

Image / Experimental Information

Image 1 DescriptionAnti-COMMD8 rabbit polyclonal antibody at 1:500 dilution Lane A: 293T Whole Cell Lysate Lane B: HEK293 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:21 kDa Observed band size:21 kDa (We are unsure as to the identity of these extra bands.)
Image 1 Alt TextHuman COMMD8 Western blot (WB) 28793
Image 1 URLSource image
Image 2 DescriptionAnti-COMMD8 rabbit polyclonal antibody at 1:500 dilution Lane A: 293T Whole Cell Lysate Lane B: HEK293 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:21 kDa Observed band size:21 kDa (We are unsure as to the identity of these extra bands.)
Image 2 Alt TextHuman COMMD8 Immunohistochemistry(IHC) 28794
Image 2 URLSource image
Image 3 DescriptionAnti-COMMD8 rabbit polyclonal antibody at 1:500 dilution Lane A: 293T Whole Cell Lysate Lane B: HEK293 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:21 kDa Observed band size:21 kDa (We are unsure as to the identity of these extra bands.)
Image 3 Alt TextHuman COMMD8 Immunoprecipitation(IP) 28795
Image 3 URLSource image

Background Information

Full NameCOMM domain containing 8
DescriptionCOMMD8 is a member of the COMMD family. Members of this family are a group of evolutionary conserved proteins that share a common COMM domain at the extreme C-terminus, which provides an interface for protein-protein interactions. Most COMMD proteins play a role in the regulation of NF˚B and, despite their similarities, seem to function in unique and non-redundant pathways. COMMD proteins may also play a role in the function of epithelial sodium channels, cell proliferation, copper homeostasis and in the regulation of the ubiquitin pathway. COMMD8 also contains 1COMM domain and is widely expressed with highest expression in thyroid.
References
  1. Danielsen JM. et al., 2011, Mol Cell Proteomics. 10 (3): M110.003590.
  2. Vinayagam A. et al., 2011, Sci Signal. 4 (189): rs8.
  3. Havugimana PC. et al., 2012, Cell. 150 (5): 1068-81.

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