| Catalog No. | Size | Price (USD) |
| 40642-T62-20 | 20 µL | $88.87 |
| 40642-T62-50 | 50 µL | $147.96 |
| 40642-T62-100 | 100 µL | $251.64 |
| 40642-T62-200 | 200 µL | $355.32 |
General Information
| Product name | Human coronavirus (HCoV-HKU1)Nucleocapsid Antibody, Rabbit PAb, Antigen Affinity Purified |
| Validated applications | WB (FAQ Protocol), ELISA (FAQ Protocol) |
| Application notes | IHC, FCM, IF, IP et al. applications haven't been validated. (Antibody's applications haven't been validated with corresponding virus positive samples. Optimal concentrations/dilutions should be determined by the end user.) |
| Specificity | HCoV-HKU1 Coronavirus Nucleocapsid |
| Immunogen | Recombinant Human coronavirus (HCoV-HKU1) Nucleoprotein / NP Protein (Catalog#40642-V07E) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human coronavirus (HCoV-HKU1) Nucleoprotein / NP (Catalog#40642-V07E; YP_173242.1; Met1-Ala441). Coronavirus Nucleocapsid specific IgG was purified by Human coronavirus (HCoV-HKU1) Nucleoprotein / NP affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Image / Experimental Information
| Image 1 Description | Anti-HCoV HKU1 NP rabbit polyclonal antibody at 1:2000 dilution. Sample：Human coronavirus (HCoV-HKU1) Nucleoprotein / NP Protein Lane A: 5ng Lane B: 1ng Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution Developed using the ECL technique. Performed under reducing conditions. |
| Image 1 Alt Text | HCoV-HKU1 Coronavirus Nucleocapsid Western blot (WB) 31747 |
| Image 1 URL | Source image |
Background Information
| Description | Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. The coronavirus N protein is required for coronavirus RNA synthesis and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is the most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to the formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of the N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool. |
| References |
|
title: MELK inhibition disrupts actin cytoskeleton and broadly restricts human coronavirus infections.
authors: Kuai Yu; Qiaorui Yao; ...; Jincun Zhao
journal: Nature Communications
date: 2026-05-06
pmid: 42091603
doi: 10.1038/s41467-026-72615-1
cited_by_count: 0
bioz_score: 94
title: A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses
authors: Chunyu Cheng; Jing Sun; ...; Yan Li
journal: Advanced Science
date: 2025-12-07
pmid: 41353654
cited_by_count: 0
techniques: Ex Vivo; Expressing; Flow Cytometry; Fluorescence; Imaging; Immunofluorescence; Immunohistochemical staining; Infection; Microscopy; Staining; Synthesized; Two Tailed Test; Virus
bioz_score: 94
