Recombinant Rat Carboxypeptidase A2 Protein (Catalog#80715-R08H)
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Rat Carboxypeptidase A2 (rR Carboxypeptidase A2; Catalog#80715-R08H; NP_001013101.2; Met1-Tyr417).
Source
Monoclonal Rabbit IgG Clone #104
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Carboxypeptidase A2 ( CPA2 ) is a secreted pancreatic procarboxy -peptidase, and cleaves the C-terminal amide or ester bond of peptides that have a free C-terminal carboxyl group. The hydrolytic action of CPA2 was identified with a preference towards long substrates with aromatic amino acids in their C-terminal end, particularly tryptophan. CPA2 comprises a signal peptide, a pro region and a mature chain, and can be activated after cleavage of the pro peptide. Three different forms of human pancreatic procarboxypeptidase A have been isolated, and the A1 and A2 forms are always secreted as monomeric proteins with different biochemical properties.
References
Catasus, L. et al., 1995. J. Biol. Chem. 270: 6651-6657.
Aloy, P. et al., 1998, Biol. Chem. 379: 149-155.
Laethem, RM. et al., 1996, Arch. Biochem. Biophys.332: 8-18.