| Catalog No. | Size | Price (USD) |
| 200709-T10-50 | 50 µL | $147.96 |
| 200709-T10-100 | 100 µL | $251.64 |
| 200709-T10-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-CRIPT Antibody, Rabbit Polyclonal |
| Validated applications | IHC-P (FAQ Protocol), ICC/IF (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human CRIPT |
| Immunogen | E. coli-derived Human CRIPT fragment |
| Preparation | Produced in rabbits immunized with E. coli-derived Human CRIPT fragment, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | PBS, pH7.0 with 0.03% Proclin300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-HSPC139 Antibody; Anti-RTS3 Antibody; Anti-SSMDF Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining of human CRIPT in human liver with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections. |
| Image 1 Alt Text | Human CRIPT Immunohistochemistry(IHC) 24663 |
| Image 1 URL | Source image |
| Image 2 Description | Immunochemical staining of human CRIPT in human liver with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections. |
| Image 2 Alt Text | Human CRIPT Immunofluorescence(IF) 24664 |
| Image 2 URL | Source image |
Background Information
| Full Name | cysteine-rich PDZ-binding protein |
| Description | CRIPT, also known as cysteine-rich PDZ-binding protein, belongs to the CRIPT family. It interacts with TUBB1. CRIPT also interacts strongly with the PDZ3 domain of members of the DLG4 family. It is involved in the cytoskeletal anchoring of DLG4 in excitatory synapses. CRIPT is highly conserved from mammals to plants and binds selectively to the third PDZ domain (PDZ3) of PSD-95 via its C terminus. n heterologous cells, CRIPT causes a redistribution of PSD-95 to microtubules. In brain, CRIPT colocalizes with PSD-95 in the postsynaptic density and can be coimmunoprecipitated with PSD-95 and tubulin. These findings suggest that CRIPT may regulate PSD-95 interaction with a tubulin-based cytoskeleton in excitatory synapses. |
| References |
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