Anti-CRTAP Antibody, Rabbit Polyclonal sinobiological 201299-T10
$243.00
In stock
SKU
201299-T10
| Catalog No. | Size | Price (USD) |
| 201299-T10-100 | 100 µL | $251.64 |
General Information
| Product name | Anti-CRTAP Antibody, Rabbit Polyclonal |
| Validated applications | IHC-P (FAQ Protocol), ICC/IF (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human CRTAP |
| Immunogen | E. coli-derived Human CRTAP fragment |
| Preparation | Produced in rabbits immunized with E. coli-derived Human CRTAP fragment, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | PBS, pH7.0 with 0.03% Proclin300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-CASP Antibody; Anti-LEPREL3 Antibody; Anti-OI7 Antibody; Anti-P3H5 Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining of human CRTAP in human liver with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections. |
| Image 1 Alt Text | Human CRTAP Immunohistochemistry(IHC) 36420 |
| Image 1 URL | Source image |
| Image 2 Description | Immunochemical staining of human CRTAP in human liver with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections. |
| Image 2 Alt Text | Human CRTAP Immunohistochemistry(IHC) 36421 |
| Image 2 URL | Source image |
| Image 3 Description | Immunochemical staining of human CRTAP in human liver with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections. |
| Image 3 Alt Text | Human CRTAP Immunofluorescence(IF) 36422 |
| Image 3 URL | Source image |
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-HD17JA0411-100-U2OS-IF.png){kind=link}
Background Information
| Description | Cartilage-associated protein (CRTAP) is an essential cofactor for the proper post-translational chain modification and collagen folding. The cartilage-associated protein (CRTAP) is part of a heterotrimeric complex (together with prolyl-3-hydroxylase-1 [P3H1] and cyclophilin B) that 3-hydroxylates the alpha 1 chain of collagen type I at proline residue 986 and plays a collagen chaperon role. CRTAP mutations lead mice (Crtap-/- mice) and humans (OI type VII) to a severe/lethal osteochondrodystrophy; patients have fractures at birth, deformities of the lower extremities and impaired growth. |
| References |
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