Anti-CUTC Antibody, Rabbit Polyclonal sinobiological 203584-T08
$243.00
In stock
SKU
203584-T08
| Catalog No. | Size | Price (USD) |
| 203584-T08-100 | 100 µL | $251.64 |
General Information
| Product name | Anti-CUTC Antibody, Rabbit Polyclonal |
| Validated applications | IHC-P (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human CUTC |
| Immunogen | E. coli-derived Human CUTC fragment |
| Preparation | Produced in rabbits immunized with E. coli-derived Human CUTC fragment, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | PBS, pH7.0 with 0.03% Proclin300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-CGI-32 Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining of human CUTC in human muscle with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections. |
| Image 1 Alt Text | Human CUTC Immunohistochemistry(IHC) 40374 |
| Image 1 URL | Source image |
| Image 2 Description | Immunochemical staining of human CUTC in human muscle with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections. |
| Image 2 Alt Text | Human CUTC Immunohistochemistry(IHC) 40375 |
| Image 2 URL | Source image |
-HD18MA0436-100-human- muscle-IHC-P.png){kind=link}
-HD18MA0436-100-human-testis-IHC-P.png){kind=link}
Background Information
| Full Name | cutC copper transporter |
| Description | Copper homeostasis protein cutC homolog, also known as CGI-32 and CUTC, is a cytoplasm and nucleus protein which belongs to theCutC family. CUTC may play a role in copper homeostasis. It can bind one Cu1+per subunit. Copper is an essential trace element to life and particularly plays a pivotal role in the physiology of aerobic organisms. Copper is a micronutrient that is required for proper metabolic functioning of most prokaryotic and eukaryotic organisms. To sustain an adequate supply of copper, a cell requires molecular mechanisms that control the metal content to avoid copper toxicity. This toxicity comes primarily from the reactivity of copper, which can lead to the generation of free radicals. In bacteria, two independent systems are responsible for maintaining the balance of copper within the cells ( Cop and Cut family proteins ). The Cut protein family is associated with copper homeostasis and involved in uptake, storage, delivery, and efflux of copper. CutC is a member of the Cut family and is suggested to be involved in efflux trafficking of cuprous ion. CutC is able to respond transcriptionally to copper and to participate in the control of copper homeostasis in E. faecalis. |
| References |
|
Reviews
Write Your Own Review