| Catalog No. | Size | Price (USD) |
| 201099-T46-50 | 50 µL | $147.96 |
| 201099-T46-100 | 100 µL | $251.64 |
| 201099-T46-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-Cyclin A2/CCNA2 Antibody, Rabbit Polyclonal |
| Validated applications | WB (FAQ Protocol), IHC-P (FAQ Protocol), ICC/IF (FAQ Protocol), IP (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human Cyclin A2/CCNA2 |
| Immunogen | E. coli-derived Human Cyclin A2 / CCNA2 fragment |
| Preparation | Produced in rabbits immunized with E. coli-derived Human Cyclin A2 / CCNA2 fragment, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | PBS, pH7.0 with 0.03% Proclin300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-CCN1 Antibody; Anti-CCNA Antibody
Image / Experimental Information
| Image 1 Description | Anti- CCNA2 rabbit polyclonal antibody at 1:500 dilution Lane A: U2OS Whole Cell Lysate Lane B: 293T Whole Cell Lysate Lane C: Cos-7 Whole Cell Lysate Lane D: HeLa Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:48 kDa Observed band size:55 kDa |
| Image 1 Alt Text | Human Cyclin A2 / CCNA2 Western blot (WB) 28917 |
| Image 1 URL | Source image |
| Image 2 Description | Anti- CCNA2 rabbit polyclonal antibody at 1:500 dilution Lane A: U2OS Whole Cell Lysate Lane B: 293T Whole Cell Lysate Lane C: Cos-7 Whole Cell Lysate Lane D: HeLa Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:48 kDa Observed band size:55 kDa |
| Image 2 Alt Text | Human Cyclin A2 / CCNA2 Immunohistochemistry(IHC) 28918 |
| Image 2 URL | Source image |
| Image 3 Description | Anti- CCNA2 rabbit polyclonal antibody at 1:500 dilution Lane A: U2OS Whole Cell Lysate Lane B: 293T Whole Cell Lysate Lane C: Cos-7 Whole Cell Lysate Lane D: HeLa Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:48 kDa Observed band size:55 kDa |
| Image 3 Alt Text | Human Cyclin A2 / CCNA2 Immunohistochemistry(IHC) 28919 |
| Image 3 URL | Source image |
| Image 4 Description | Anti- CCNA2 rabbit polyclonal antibody at 1:500 dilution Lane A: U2OS Whole Cell Lysate Lane B: 293T Whole Cell Lysate Lane C: Cos-7 Whole Cell Lysate Lane D: HeLa Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:48 kDa Observed band size:55 kDa |
| Image 4 Alt Text | Human Cyclin A2 / CCNA2 Immunofluorescence(IF) 28920 |
| Image 4 URL | Source image |
| Image 5 Description | Anti- CCNA2 rabbit polyclonal antibody at 1:500 dilution Lane A: U2OS Whole Cell Lysate Lane B: 293T Whole Cell Lysate Lane C: Cos-7 Whole Cell Lysate Lane D: HeLa Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:48 kDa Observed band size:55 kDa |
| Image 5 Alt Text | Human Cyclin A2 / CCNA2 Immunoprecipitation(IP) 28921 |
| Image 5 URL | Source image |
Background Information
| Full Name | cyclin A2 |
| Description | CCNA2 (also known as CyclinA2) belongs to the highly conserved cyclin family and is significantly overexpressed in various cancer types. CCNA2 had significant predictive power in distant metastasis free survival, disease free survival, recurrence free survival and overall survival of ER+ breast cancer patients. We also found that CCNA2 was closely associated with tamoxifen resistance. CCNA2 is a biomarker for the prognosis of ER+ breast cancer and monitoring of tamoxifen efficacy. CCNA2 gene plays an important role in hair follicle initiation and development, and it is involved in the distinctive wool density of the Rex rabbit. It is an important candidate gene for wool density selection through marker-assisted selection. |
| Related Pathways |
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