Anti-DDB1 Antibody, Rabbit Polyclonal sinobiological 201437-T46

$143.00
In stock
SKU
201437-T46
Catalog No.SizePrice (USD)
201437-T46-5050 µL$147.96
201437-T46-100100 µL$251.64
201437-T46-200200 µL$355.32

General Information

Product nameAnti-DDB1 Antibody, Rabbit Polyclonal
Validated applicationsWB (FAQ Protocol), IHC-P (FAQ Protocol), ICC/IF (FAQ Protocol), IP (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman DDB1
ImmunogenE. coli-derived Human DDB1 fragment
PreparationProduced in rabbits immunized with E. coli-derived Human DDB1 fragment, and purified by antigen affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A & Antigen Affinity
FormulationPBS, pH7.0 with 0.03% Proclin300
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-DDBA Antibody; Anti-UV-DDB1 Antibody; Anti-WHIKERS Antibody; Anti-XAP1 Antibody; Anti-XPCE Antibody; Anti-XPE Antibody; Anti-XPE-BF Antibody

Image / Experimental Information

Image 1 DescriptionAnti-DDB1 rabbit polyclonal antibody at 1:500 dilution Lane A: HeLa Whole Cell Lysate Lane B: Jurkat Whole Cell Lysate Lane C: K562 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:127 kDa Observed band size:127 kDa
Image 1 Alt TextHuman DDB1 Western blot (WB) 29475
Image 1 URLSource image
Image 2 DescriptionAnti-DDB1 rabbit polyclonal antibody at 1:500 dilution Lane A: HeLa Whole Cell Lysate Lane B: Jurkat Whole Cell Lysate Lane C: K562 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:127 kDa Observed band size:127 kDa
Image 2 Alt TextHuman DDB1 Immunohistochemistry(IHC) 29476
Image 2 URLSource image
Image 3 DescriptionAnti-DDB1 rabbit polyclonal antibody at 1:500 dilution Lane A: HeLa Whole Cell Lysate Lane B: Jurkat Whole Cell Lysate Lane C: K562 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:127 kDa Observed band size:127 kDa
Image 3 Alt TextHuman DDB1 Immunohistochemistry(IHC) 29477
Image 3 URLSource image
Image 4 DescriptionAnti-DDB1 rabbit polyclonal antibody at 1:500 dilution Lane A: HeLa Whole Cell Lysate Lane B: Jurkat Whole Cell Lysate Lane C: K562 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:127 kDa Observed band size:127 kDa
Image 4 Alt TextHuman DDB1 Immunofluorescence(IF) 29478
Image 4 URLSource image
Image 5 DescriptionAnti-DDB1 rabbit polyclonal antibody at 1:500 dilution Lane A: HeLa Whole Cell Lysate Lane B: Jurkat Whole Cell Lysate Lane C: K562 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:127 kDa Observed band size:127 kDa
Image 5 Alt TextHuman DDB1 Immunoprecipitation(IP) 29479
Image 5 URLSource image

Background Information

Full Namedamage specific DNA binding protein 1
DescriptionDNA damage-binding protein 1 (DDB1) is a large subunit of the heterodimeric DDB complex that recognizes DNA lesions and initiates the nucleotide excision repair process. DDB1 is also a component of the CUL4 E3 ligase complex involved in a broad spectrum of cellular processes by targeted ubiquitination of key regulators. A subclass of DDB1 (damaged DNA binding protein-1)-binding WD40-repeat domain (DWD) family proteins has been demonstrated to function as the substrate recognition subunits of the cullin4-ring ubiquitin E3 ligase complex.

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