| Catalog No. | Size | Price (USD) |
| 203094-T02-50 | 50 µL | $147.96 |
| 203094-T02-100 | 100 µL | $251.64 |
| 203094-T02-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-DPF2 Antibody, Rabbit Polyclonal |
| Validated applications | ICC/IF (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human DPF2 |
| Immunogen | E. coli-derived Human DPF2 fragment |
| Preparation | Produced in rabbits immunized with E. coli-derived Human DPF2 fragment, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | PBS, pH7.0 with 0.03% Proclin300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-BAF45D Antibody; Anti-CSS7 Antibody; Anti-REQ Antibody; Anti-SMARCG2 Antibody; Anti-ubi-d4 Antibody; Anti-UBID4 Antibody
Image / Experimental Information
| Image 1 Description | Immunofluorescence staining of DPF2 in A431 cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS,blocked with 10% serum, and incubated with rabbit anti-Human DPF2 polyclonal antibody (dilution ratio 1:100) at 4℃ overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to Nucleus and Cytoplasm. |
| Image 1 Alt Text | Human DPF2 Immunofluorescence(IF) 33404 |
| Image 1 URL | Source image |
Background Information
| Full Name | double PHD fingers 2 |
| Description | The d4-protein family is characterized by an N-terminal 2/3 domain, a C2H2-type zinc finger (ZF), and a C-terminal tandem PHD zinc finger. The d4 family of transcription factors consists of three members in mammals. DPF1/neuro-d4 is expressed mainly in neurons and the peripheral nervous system, and is important for brain development. DPF2/requiem/ubi-d4 is expressed ubiquitously and presumably functions as an apoptotic factor, especially during the deprivation of trophic factors. Double plant homeodomain finger 2 (DPF2) is a highly evolutionarily conserved member of the d4 protein family that is ubiquitously expressed in human tissues and was recently shown to inhibit the myeloid differentiation of hematopoietic stem/progenitor and acute myelogenous leukemia cells. The histone binding of DPF2 plays an important regulatory role in the transcriptional program that drives myeloid differentiation. DPF3/cer-d4 is expressed in neurons and the heart, and is important for heart development and function in zebrafish. In Drosophila, there is only one member, dd4, whose function is still unknown, but it is expressed in many tissues and is particularly abundant in the brain of developing embryos and in adults. |
| References |
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