| Catalog No. | Size | Price (USD) |
| 100592-T36-50 | 50 µL | $147.96 |
| 100592-T36-100 | 100 µL | $251.64 |
| 100592-T36-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-DPP6 Antibody, Rabbit Polyclonal |
| Validated applications | WB (FAQ Protocol), IP (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human DPP6 |
| Immunogen | A synthetic peptide corresponding to the center region of the Human DPP6 |
| Preparation | Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human DPP6, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-DPL1 Antibody; Anti-DPPX Antibody; Anti-MRD33 Antibody; Anti-VF2 Antibody
Image / Experimental Information
| Image 1 Description | Anti-DPP6 rabbit monoclonal antibody at 1:500 dilution Lane A: Rat brain tissue lysate Lane B: Mouse brain tissue lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:98 kDa Observed band size:115 kDa |
| Image 1 Alt Text | Human DPP6 Western blot (WB) 34782 |
| Image 1 URL | Source image |
| Image 2 Description | Anti-DPP6 rabbit monoclonal antibody at 1:500 dilution Lane A: Rat brain tissue lysate Lane B: Mouse brain tissue lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:98 kDa Observed band size:115 kDa |
| Image 2 Alt Text | Human DPP6 Immunoprecipitation(IP) 34783 |
| Image 2 URL | Source image |
Background Information
| Full Name | dipeptidyl-peptidase 6 |
| Description | Dipeptidyl peptidase-like protein 6 (DPP6), a member of the dipeptidyl aminopeptidase family, plays distinct roles in brain development. Dipeptidyl peptidase-like protein 6 (DPP6) is an auxiliary subunit of the Kv4 family of voltage-gated K(+) channels known to enhance channel surface expression and potently accelerate their kinetics. DPP6 is a single transmembrane protein, which is structurally remarkable for its large extracellular domain. DPP6 is well known as an auxiliary subunit of Kv4-containing, A-type K(+) channels which regulate dendritic excitability in hippocampal CA1 pyramidal neurons. We have recently reported, however, a novel role for DPP6 in regulating dendritic filopodia formation and stability, affecting synaptic development and function. |
| Research Areas |
|
title: Activity-dependent degradation of Kv4.2 contributes to synaptic plasticity and behavior in Angelman syndrome model mice
authors: Jia-Hua Hu; Cole Malloy; ...; Dax A. Hoffman
journal: Cell Reports
date: 2025-05-27
pmid: 40310720
cited_by_count: 2
bioz_score: 93
-HD16AU0510-WB.png){kind=link}
