Anti-Dusp23 Antibody, Rabbit Polyclonal sinobiological 202743-T10
$243.00
In stock
SKU
202743-T10
| Catalog No. | Size | Price (USD) |
| 202743-T10-100 | 100 µL | $251.64 |
General Information
| Product name | Anti-Dusp23 Antibody, Rabbit Polyclonal |
| Validated applications | IHC-P (FAQ Protocol), ICC/IF (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human Dusp23 |
| Immunogen | E. coli-derived Human Dusp23 fragment |
| Preparation | Produced in rabbits immunized with E. coli-derived Human Dusp23 fragment, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-DUSP23 Antibody; Anti-DUSP25 Antibody; Anti-FLJ20442 Antibody; Anti-LDP-3 Antibody; Anti-LDP3 Antibody; Anti-MOSP Antibody; Anti-VHZ Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining of human Dusp23 in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections. |
| Image 1 Alt Text | Human Dusp23 Immunohistochemistry(IHC) 36438 |
| Image 1 URL | Source image |
| Image 2 Description | Immunochemical staining of human Dusp23 in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections. |
| Image 2 Alt Text | Human Dusp23 Immunofluorescence(IF) 36439 |
| Image 2 URL | Source image |
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Background Information
| Full Name | dual specificity phosphatase 23 |
| Description | DUSPs (dual-specificity phosphatases) are a heterogeneous group of protein phosphatases that can dephosphorylate both phosphotyrosine and phosphoserine/phosphothreonine residues within the one substrate. DUSPs have been implicated as major modulators of critical signalling pathways that are dysregulated in various diseases. DUSP23 is a low molecular weight DUSP that lacks the N-terminal domain of mitogen-activated protein kinase phosphatases (MKPs). DUSP23 and other low molecular weight DUSPs, such as DUSP3 and DUSP22, are structurally similar to the vaccinia virus VH1 phosphatase. DUSP3, DUSP22 and VH1 participate in both the interferon (IFN) and interleukin-signalling pathways by dephosphorylating signal transducer and activator of transcription (STAT) proteins. |
| References |
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