Anti-EBAG9 Antibody, Rabbit Polyclonal sinobiological 310899-T10

$143.00
In stock
SKU
310899-T10
Catalog No.SizePrice (USD)
310899-T10-5050 µL$147.96
310899-T10-100100 µL$251.64
310899-T10-200200 µL$355.32

General Information

Product nameAnti-EBAG9 Antibody, Rabbit Polyclonal
Validated applicationsIHC-P (FAQ Protocol), ICC/IF (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman EBAG9
ImmunogenE. coli-derived Human EBAG9 fragment
PreparationProduced in rabbits immunized with E. coli-derived Human EBAG9 fragment, and purified by antigen affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A & Antigen Affinity
FormulationPBS, pH7.0 with 0.03% Proclin300
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-EB9 Antibody; Anti-PDAF Antibody; Anti-RCAS1 Antibody

Image / Experimental Information

Image 1 DescriptionImmunochemical staining of human EBAG9 in human brain with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
Image 1 Alt TextHuman EBAG9 Immunohistochemistry(IHC) 32267
Image 1 URLSource image
Image 2 DescriptionImmunochemical staining of human EBAG9 in human brain with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
Image 2 Alt TextHuman EBAG9 Immunofluorescence(IF) 32268
Image 2 URLSource image

Background Information

Full Nameestrogen receptor binding site associated, antigen, 9
DescriptionRCAS1, also known as EBAG9, is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. RCAS1 gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen is mediated by estrogen receptor which binds to the estrogen-responsive element (ERE) found in the 5'-flanking region of RCAS1 gene. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for RCAS1 gene. EBAG9 may participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.
References
  1. Ohshima K. et al., 2001, Clin Exp Immunol. 123 (3): 481-6.
  2. Ikeda K. et al., 2000, Biochem Biophys Res Commun. 273 (2): 654-60.
  3. Nakashima M. et al., 1999, Nat Med. 5 (8): 938-42.

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