| Catalog No. | Size | Price (USD) |
| 206812-T08-50 | 50 µL | $147.96 |
| 206812-T08-100 | 100 µL | $251.64 |
| 206812-T08-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-EBPL Antibody, Rabbit Polyclonal |
| Validated applications | IHC-P (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human EBPL |
| Immunogen | E. coli-derived Human EBPL fragment |
| Preparation | Produced in rabbits immunized with E. coli-derived Human EBPL fragment, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | PBS, pH7.0 with 0.03% Proclin300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-EBRP Antibody; Anti-ERP Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining of human EBPL in human liver with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections. |
| Image 1 Alt Text | Human EBPL Immunohistochemistry(IHC) 26798 |
| Image 1 URL | Source image |
| Image 2 Description | Immunochemical staining of human EBPL in human liver with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections. |
| Image 2 Alt Text | Human EBPL Immunohistochemistry(IHC) 26799 |
| Image 2 URL | Source image |
| Image 3 Description | Immunochemical staining of human EBPL in human liver with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections. |
| Image 3 Alt Text | Human EBPL Immunohistochemistry(IHC) 26800 |
| Image 3 URL | Source image |
Background Information
| Description | EBP (emopamil-binding protein) is a high-affinity binding protein for [3H]emopamil and belongs to the family of so-called sigma receptors. Mutations that disrupt EBP's 3beta-hydroxysteroid sterol delta8-delta7 isomerase activity (EC 5.3.3.5) impair cholesterol biosynthesis and cause X-chromosomal dominant chondrodysplasia punctata. Based on amino acid sequence alignments, EBPL (EBP-like protein) is distantly related to EBP (31% identity and 52% similarity) and found in animals but not in plants. EBPL is encoded by four exons on human chromosome 13q14.2 covering 30.7 kb, and a partially processed EBPL pseudogene was found on 16q21. The EBPL mRNA was expressed ubiquitously and most abundant in liver, lung and kidney. |
| References |
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