| Catalog No. | Size | Price (USD) |
| 201972-T02-50 | 50 µL | $147.96 |
| 201972-T02-100 | 100 µL | $251.64 |
| 201972-T02-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-AGR3 Antibody, Rabbit Polyclonal |
| Validated applications | ICC/IF (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human AGR3 |
| Immunogen | E. coli-derived Human AGR3 fragment |
| Preparation | Produced in rabbits immunized with E. coli-derived Human AGR3 fragment, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | PBS, pH7.0 with 0.03% Proclin300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-AG-3 Antibody; Anti-AG3 Antibody; Anti-BCMP11 Antibody; Anti-hAG-3 Antibody; Anti-HAG3 Antibody; Anti-PDIA18 Antibody; Anti-UNQ642/PRO1272 Antibody
Image / Experimental Information
| Image 1 Description | Immunofluorescence staining of AGR3 in U2OS cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS,blocked with 10% serum, and incubated with rabbit anti-Human AGR3 polyclonal antibody (dilution ratio 1:100) at 4℃ overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue).Positive staining was localized to Cytoplasm. |
| Image 1 Alt Text | Human AGR3 Immunofluorescence(IF) 22901 |
| Image 1 URL | Source image |
Background Information
| Full Name | anterior gradient 3 |
| Description | Anterior gradient protein (AGR) 3 is a highly related homologue of pro-oncogenic AGR2 and belongs to the family of protein disulfide isomerases. AGR3 was found in breast, ovary, prostate, and liver cancer, it is associated with the level of differentiation, slowly proliferating tumors, and more favorable prognosis of breast cancer patients. AGR3 is a specialized member of the PDI family that plays an unexpected role in the regulation of CBF and mucociliary clearance in the airway. AGR3 had been characterised as a novel potential biomarker both for breast cancer prognosis and early breast cancer detection from blood. |
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