Recombinant Anti-Erythropoietin R/EPOR Antibody (HRP), Rabbit Monoclonal sinobiological 10707-R010-H

$500.00
In stock
SKU
10707-R010-H
Catalog No.SizePrice (USD)
10707-R010-H-100100 µg$518.39

General Information

Product nameRecombinant Anti-Erythropoietin R/EPOR Antibody (HRP), Rabbit Monoclonal
Validated applicationsELISA (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman Erythropoietin R/EPOR
ImmunogenRecombinant Human EPOR Protein (Catalog#10707-H08H)
PreparationThis antibody was obtained from a rabbit immunized with purified, recombinant Human EPOR (rh EPOR; Catalog#10707-H08H; Met 1-Pro 250; NP_000112.1), and conjugated with horseradish-peroxidase (HRP).
SourceMonoclonal Rabbit IgG Clone #010
PurificationProtein A
Formulation0.2 μm filtered solution in PBS
ConjugateHRP
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Protected from prolonged exposure to light. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-EPO-R Antibody

Background Information

Full Nameerythropoietin receptor
DescriptionErythropoietin (EPO) is the major glycoprotein hormone regulator of mammalian erythropoiesis, and is produced by kidney and liver in an oxygen-dependent manner. The biological effects of EPO are mediated by the specific erythropoietin receptor (EPOR/EPO Receptor) on bone marrow erythroblasts, which transmits signals important for both proliferation and differentiation along the erythroid lineage. EPOR protein is a type â… single-transmembrane cytokine receptor, and belongs to the homodimerizing subclass which functions as ligand-induced or ligand-stabilized homodimers. EPOR signaling prevents neuronal death and ischemic injury. Recent studies have shown that EPO and EPOR protein may be involved in carcinogenesis, angiogenesis, and invasion.
References
  1. Divoky V, et al. (2002) Mouse surviving solely on human erythropoietin receptor (EpoR): model of human EpoR-linked disease. Blood 99(10): 3873-4.
  2. Carruthers SG. (2009) A truncated erythropoietin receptor EPOR-T is associated with hypertension susceptibility. Clin Pharmacol Ther. 86(2): 134-6.
  3. Baltaziak M, et al. (2009) Relationships of P53 and Bak with EPO and EPOR in human colorectal cancer. Anticancer Res. 29(10):4151-6.

Reviews

Write Your Own Review
You're reviewing:Recombinant Anti-Erythropoietin R/EPOR Antibody (HRP), Rabbit Monoclonal sinobiological 10707-R010-H
Your Rating
Copyright © 2025 Biogege, Inc. All rights reserved.