| Catalog No. | Size | Price (USD) |
| 207497-T02-50 | 50 µL | $147.96 |
| 207497-T02-100 | 100 µL | $251.64 |
| 207497-T02-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-ERRα/ESRRA Antibody, Rabbit Polyclonal |
| Validated applications | ICC/IF (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human ERRα/ESRRA |
| Immunogen | E. coli-derived Human Estrogen Related Receptor alpha / ESRRA fragment |
| Preparation | Produced in rabbits immunized with E. coli-derived Human Estrogen Related Receptor alpha / ESRRA fragment, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | PBS, pH7.0 with 0.03% Proclin300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-ERR1 Antibody; Anti-ERRa Antibody; Anti-ERRalpha Antibody; Anti-ESRL1 Antibody; Anti-NR3B1 Antibody
Image / Experimental Information
| Image 1 Description | Immunofluorescence staining of Estrogen Related Receptor alpha in MCF7 cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS,blocked with 10% serum, and incubated with rabbit anti-Human Estrogen Related Receptor alpha polyclonal antibody (dilution ratio 1:200) at 4℃ overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to Nucleus and Cytoplasm. |
| Image 1 Alt Text | Human Estrogen Related Receptor alpha Immunofluorescence(IF) 26611 |
| Image 1 URL | Source image |
Background Information
| Full Name | estrogen-related receptor alpha |
| Description | The orphan nuclear receptor ESRRA (estrogen-related receptor alpha) is a key regulator of energy homeostasis and mitochondrial function. ESRRA as a critical activator of autophagy via both transcriptional and post-translational control to promote antimicrobial host responses. Anorexia nervosa and bulimia nervosa are common and severe eating disorders (EDs), and the ESRRA mutations result in decreased ESRRA activity increase the risk of developing EDs. |
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