Anti-FABP5 Antibody, Rabbit Polyclonal sinobiological 12581-T20

$143.00
In stock
SKU
12581-T20
Catalog No.SizePrice (USD)
12581-T20-5050 µL$147.96
12581-T20-100100 µL$251.64
12581-T20-200200 µL$355.32

General Information

Product nameAnti-FABP5 Antibody, Rabbit Polyclonal
Validated applicationsELISA (FAQ Protocol), IP (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman FABP5
ImmunogenRecombinant Human FABP5 Protein (Catalog#12581-HNAE)
PreparationProduced in rabbits immunized with purified, recombinant Human FABP5 (rh FABP5; Catalog#12581-HNAE; Q01469; Met1-Glu135). FABP5 specific IgG was purified by Human FABP5 affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A & Antigen Affinity
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-E-FABP Antibody; Anti-EFABP Antibody; Anti-KFABP Antibody; Anti-PA-FABP Antibody; Anti-PAFABP Antibody

Image / Experimental Information

Image 1 DescriptionFABP5 was immunoprecipitated using: Lane A:0.5 mg HeLa Whole Cell Lysate Lane B:0.5 mg A431 Whole Cell Lysate Lane C:0.5 mg HepG2 Whole Cell Lysate 4 µL anti-FABP5 rabbit polyclonal antibody and 60 μg of Immunomagnetic beads Protein A/G. Primary antibody: Anti-FABP5 rabbit polyclonal antibody,at 1:100 dilution Secondary antibody: Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution Developed using the ECL technique. Performed under reducing conditions. Predicted band size: 15 kDa Observed band size :15 kDa
Image 1 Alt TextHuman FABP5 Immunoprecipitation(IP) 35313
Image 1 URLSource image

Background Information

Full Namefatty acid binding protein 5 (psoriasis-associated)
DescriptionFatty acid-binding protein, also known as Epidermal-type fatty acid-binding protein, Fatty acid-binding protein 5, Psoriasis-associated fatty acid-binding protein homolog, E-FABP and FABP5, is a cytoplasm protein which Belongs to thecalycin superfamily and Fatty-acid binding protein (FABP) family. Fatty acid-binding proteins ( FABPs ) are postulated to serve as lipid shuttles that solubilize hydrophobic fatty acids and deliver them to appropriate intracellular sites. E-FABP / FABP5 is predominantly expressed in keratinocytes and is overexpressed in the actively proliferating tissue characteristic of psoriasis and wound healing. E-FABP / FABP5 exhibits an important role in binding free fatty acids, as well as regulating lipid metabolism and transport. E-FABP / FABP5 has high specificity for fatty acids. It has highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity of FABP5. E-FABP / FABP5 may be involved in keratinocyte differentiation.
References
  1. Hohoff C., et al., 1999, Biochemistry 38:12229-39
  2. Gutierrez-Gonzalez L.H., et al., 2002, Biochem. J. 364:725-37.
  3. Ogawa,E. et al., 2011, J Invest Dermatol. 131 (3):604-12.
  4. Ma,X. et al., 2010, Mol Biol Rep. 37 (8):4003-11.

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