| Catalog No. | Size | Price (USD) |
| 310726-T08-50 | 50 µL | $147.96 |
| 310726-T08-100 | 100 µL | $251.64 |
| 310726-T08-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-Factor D Antibody, Rabbit Polyclonal |
| Validated applications | IHC-P (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human Factor D |
| Immunogen | E. coli-derived Human Factor D fragment |
| Preparation | Produced in rabbits immunized with E. coli-derived Human Factor D fragment, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | PBS, pH7.0 with 0.03% Proclin300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-ADIPSIN Antibody; Anti-ADN Antibody; Anti-DF Antibody; Anti-PFD Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining of human Factor D in human lung cancer with rabbit polyclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections. |
| Image 1 Alt Text | Human Factor D Immunohistochemistry(IHC) 29722 |
| Image 1 URL | Source image |
Background Information
| Full Name | complement factor D (adipsin) |
| Description | Complement factor D, also known as Adipsin, C3 convertase activator, Properdin factor D and CFD is a secreted protein which belongs to thepeptidase S1 family. CFD / Adipsin contains onepeptidase S1 domain. Complement factor D ( CFD / Adipsin ) is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. Complement factor D ( CFD / Adipsin ) has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology. This protein is also a serine protease that is secreted by adipocytes into the bloodstream. Complement factor D ( CFD / Adipsin ) cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. Complement factor D ( CFD / Adipsin ) is a serine protease that stimulates glucose transport for triglyceride accumulation in fats cells and inhibits lipolysis. Defects in CFD / Adipsin are the cause of complement factor D deficiency (CFD deficiency) which predisposes to invasive meningococcal disease. |
| Related Pathways |
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| References |
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